 | | Vol. 13.11 – 24 March, 2022 |
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| Investigators developed in vitro methods using a kidney decellularized ECM hydrogel to culture human pluripotent stem cell-derived kidney organoids, which had extensive vascular network and their own endothelial cells.
[Advanced Science] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers fabricated poly(ε-caprolactone) fiber skeletons (PSs) that were subcutaneously embedded to induce the assembly of host cells and ECM to obtain PS-reinforced biotubes.
[Science Advances] |
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| The authors identified the class of cellular inhibitor of apoptosis protein-1/2 inhibitors as inducing cell death selectively in SOX10-deficient cells.
[Nature Communications] |
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| Investigators proposed a nanofibrillar hydrogel for the initiation and growth of breast cancer patient-derived tumor organoids.
[Nature Communications] |
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| Scientists demonstrated the key role of fibroadipogenic progenitors and their cross-talk with muscle cells through a paracrine signaling pathway in fibrosis of human skeletal muscle and identified endothelin as a new druggable target to counteract human muscle fibrosis.
[Journal of Cachexia Sarcopenia and Muscle] |
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| Researchers used Dupuytren’s disease, a localized fibrotic condition of the hand, as a model to profile the vasculature niche of human fibrosis at single-cell resolution.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| Investigators showed that matrix metalloproteinase 2, which degrades type IV collagen, was abundantly expressed in human skin, increased with age in sun-exposed skin, and correlated robustly with aryl hydrocarbon receptor (AhR), a transcription factor directly activated by UV-generated photometabolites.
[JCI Insight] |
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| Scientists investigated several superabsorbent dressings for their ability to absorb and retain bacteria, their impact on bacterial viability, and their ability to sequester matrix metalloproteinases-2 and 9 over seven days.
[Scientific Reports] |
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| Ti3C2 MXene was incorporated into composite scaffolds composed of hydroxyapatite and sodium alginate via extrusion-based 3D printing to evaluate its potential in bone regeneration.
[Biomedical Materials] |
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| The authors addressed the contemporary need for a conductive biomimetic nanocomposite scaffold for cardiac tissue engineering by examining the use of a gold nanoparticle-incorporated porcine cholecystic ECM for the same.
[Journal of Biomedical Materials Research Part B-Applied Biomaterials] |
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| Researchers reported the development of an in vitro 3D breast cancer model to investigate the effect of stromal crosslinking and consequent, stiffening on the angiogenic activity of cancer cells.
[Biotechnology Progress] |
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| Scientists provide insight into the field of material-assisted strategies for osteochondral (OC) regeneration, with particular considerations for the therapeutic potential of the different approaches and current OC regeneration evaluation methods.
[Advanced Science] |
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| The authors provide an update on the regulation of noncoding RNAs in the crosstalk between macrophages and tumor cells in hepatocellular carcinoma.
[Molecular Therapy-Oncolytics] |
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| Molecular Matrix, Inc. (MMI) announced the full launch of its Osteo-P® Synthetic Bone Graft Substitute (BGS) for use in the musculoskeletal system. Osteo-P® BGS is made using MMI’s hyper-crosslinked carbohydrate polymer technology platform engineered to optimize the microenvironment for bone repair.
[Molecular Matrix, Inc. (Business Wire, Inc.)] |
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| June 5 – 10, 2022
Ventura, California, United States |
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| | Mayo Clinic – Jacksonville, Florida, United States |
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| | University of California, San Diego – La Jolla, California, United States |
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| | Icahn School of Medicine at Mount Sinai – New York City, New York, United States |
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| | Genentech, Inc. – South San Francisco, California, United States |
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| | Johns Hopkins University School of Medicine – Baltimore, Maryland, United States |
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Cancer Stem Cell News
Cell Therapy News
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