 | | Vol. 13.23 – 16 June, 2022 |
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| Scientists established a simple 3D culture system that allowed for the generation and manipulation of neuroepithelial organoids from human induced PSCs, displaying developmental phases of hiPSC differentiation and self-aggregation.
[Advanced Science] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The application of anisotropic Fe3O4 MNPs were described, and synthesized by a novel and easy route, that could be aligned on pre-defined patterns within objects printed by digital light processing, resulting in materials that can be actuated remotely.
[Advanced Functional Materials] |
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| Investigators used singe-cell RNA sequencing to define the human basal cell carcinoma ecosystem and discriminated between normal and malignant epithelial cells.
[Science Advances] |
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| Data revealed cross talk between dystrophin and focal adhesions (FAs), as the expression of wild-type or I232M dystrophin increased FA tension compared to dystrophin-less nontransgenic myoblasts.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| Scientists used BioID to interrogate the interactomes of β1 and β3 integrins in epithelial cells and identified PEAK1 as an interactor of the RGD-binding integrins α5β1, αVβ3, and αVβ5 in focal adhesions.
[Journal of Cell Biology] |
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| Proteomic analysis showed a higher abundance of the extracellular matrix small leucine-rich proteoglycan Fibromodulin in the conditioned medium of differentiated glioma cells, the equivalent of glioma non-cancer stem cells, compared to that of glioma stem-like cells.
[eLife] |
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| Researchers reported that regional intravascular infusion of ODN2395 into mice with liver metastasis partially eliminated liver myeloid-derived suppressor cells (MDSCs) and reprogrammed residual MDSC.
[Cancer Gene Therapy] |
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| The authors observe and distinguish the various roles a cellular communication network (CCN) protein may execute within distinct tumor microenvironments and the biological associations among them.
[Journal of Cell Communication and Signaling] |
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| Investigators highlight the current evidence supporting sex-specific roles for ECM signaling proteins in the brain and their associations with opioid use disorder.
[Frontiers in Integrative Neuroscience] |
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| Defeat Duchenne Canada is investing $1.14 million in three research projects aimed at providing better treatments for Duchenne muscular dystrophy, the most common type of muscular dystrophy and one that affects about 1 in 3,500 male births.
[BioNews, Inc.] |
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| October 3 – 5, 2022
Vancouver, British Columbia, Canada |
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| | Max Planck Institute of Biochemistry – Munich, Germany |
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| | Uppsala University – Uppsala, Sweden |
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| | University of California, San Francisco – San Francisco, California, United States |
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| | Stem Cell Network – Ottawa, Ontario, Canada |
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| | China Medical University – Shenyang, China |
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