| Vol. 13.28 – 21 July, 2022 |
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| The authors identified the functional impact of type I collagen (Col1) homotrimers on tumor microbiome and tumor immunity, implicating Col1 homotrimer-α3β1 integrin signaling axis as a cancer-specific therapeutic target. [Cancer Cell] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| A hyaluronic acid nanocomposite hydrogel was developed based on aldehyde-modified sodium hyaluronate, hydrazide-modified sodium hyaluronate, and aldehyde-modified cellulose nanocrystals, which exhibited improved strength and excellent self-healing ability. [ACS Nano] |
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| Scientists showed that cadherin clustering stimulated and spatially guided integrin activation. Adherens junction-associated integrin activation depended on locally generated tension and did not require ECM ligands. [Cell Reports] |
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| Researchers functionalized 3D printed 1,4 butanediol thermoplastic polyurethane (b-TPUe) scaffolds and used infrapatellar mesenchymal stem cells as the cellular source. [Advanced Healthcare Materials] |
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| RNA-Seq and qRT-PCR gene expression analyses revealed that AmrZ regulated many genes related to the production of ECM components at the transcriptional level. [Scientific Reports] |
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| Reduced dynamic loads due to hip dislocation induced acetabular cartilage degeneration via IL-6 and MMP3 through STAT3/periostin/NF-κB signaling in rodent disarticulation-developmental dysplasia of the hip models. [Scientific Reports] |
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| Adding decellularized ECM microparticles derived from porcine tracheal cartilage to gelatin-methacryloyl created a yield stress fluid capable of forming self-supporting structures. [Macromolecular Materials and Engineering] |
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| Scientists compared two physical and five chemical decellularization methods for cultured cell-derived ECM reconstructed by decellularization. [Journal of Biomedical Materials Research Part B-Applied Biomaterials] |
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| The authors summarize the current understanding of bone remodeling and future research directions with the aim of providing a clinically relevant biological background with which to identify targets for therapeutic strategies in osteoporosis. [Bone Research] |
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| Scientists summarize the roles and underlying mechanisms of myokines, such as IL-6, myostatin, IL-15, irisin, fibroblast growth factor 21, and musclin, in cancer cachexia. [Biochimica et Biophysica Acta-Reviews On Cancer] |
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| The wide variety of sources, crosslinking strategies, and functionalization methods, and mostly the resemblance of hydrogels to the natural ECM, make this 3D hydrated structure an excellent tool for tissue engineering approaches. [Macromolecular Bioscience] |
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| Acera Surgical, Inc., a bioscience company developing and commercializing a portfolio of fully synthetic materials for regenerative medical applications, announced it has entered a new phase of growth after signing an agreement with Capstone Health Alliance. [Acera Surgical, Inc. (Cision US, Inc.)] |
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| August 7-11, 2022 Treasure Drive, Nova Scotia, Canada |
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| Ohio State University Wexner Medical Center – Columbus, Ohio, United States |
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| Lehigh University – Bethlehem, Pennsylvania, Untied States |
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| Aarhus University – Aarhus, Denmark |
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| The Chinese University of Hong Kong – Hong Kong, China |
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| Uppsala University – Uppsala, Sweden |
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