 | | Vol. 13.36 – 15 September, 2022 |
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| A new strategy called FLight biofabrication rapidly created hydrogels composed of unidirectional microfilament networks, with diameters on the length scale of single cells.
[Advanced Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers found significant variations in immune cell frequency and phenotype, checkpoint expression, and collagen matrix between the malignant cell area, leading edge, and stroma of patients with advanced clear cell ovarian cancer.
[Cancer Immunology Research] |
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| Investigators demonstrated a fast in situ crosslinking of calcium phosphate oligomers on collagen matrixes for efficient organic-inorganic interface re-construction, which could result in a biomimetic hybrid.
[Advanced Healthcare Materials] |
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| Scientists designed a 3D model scaffold, based on elastin-like recombinamer hydrogels. This contained two interior and well-defined areas, small cylinders, with differentiated bioactivities with respect to the bulk.
[Advanced Healthcare Materials] |
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| The authors showed that pharmacological inhibition or knock down of MCL-1 in primary breast cancer-associated fibroblasts directly derived from human samples mitigated myofibroblastic features.
[Cell Death & Disease] |
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| Researchers found that glioma 1 and Smoothened in the Sonic Hedgehog signaling pathway were activated and that collagen‐1 and collagen‐3, which constituted the fibrotic index, were expressed in chronic kidney disease myocardial tissue.
[Journal of the American Heart Association] |
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| Investigators presented results of a molecular docking analysis showing interactions likely to have been involved in the inhibition of BMP-1 activity by Sizzled.
[Scientific Reports] |
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| Scientists developed a deep learning-based analysis pipeline for the classification of cell morphometric phenotypes from multi-channel fluorescence micrographs, termed SE-RNN.
[Scientific Reports] |
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| Investigators discuss the known functions, architecture, and regulatory mechanisms of podosomes and invadopodia.
[Nature Reviews Molecular Cell Biology] |
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| The authors discuss literature on the possible contribution of therapy-induced senescence (TIS) in tumor dormancy, provide examples on the current 3D models of senescence, and propose a novel 3D model to investigate the ultimate role of TIS in mediating overall response to therapy.
[Ageing Research Reviews] |
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| Microenvironmental cue-regulated exosomes as therapeutic strategies to improve chronic wound healing by regulating the inflammatory response, promoting cell proliferation and migration, facilitating angiogenesis, and regulating ECM remodeling are discussed.
[NPG Asia Materials] |
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| Virogin Biotech and The University of Texas MD Anderson Cancer Center announced a strategic collaboration to accelerate the development of investigational treatments, including oncolytic viruses and immunotherapies, for patients with advanced cancers.
[Virogin Biotech (Globe Newswire, Inc.)] |
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| December 12 – 13, 2022
Ghent, Belgium |
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| | National University of Ireland Galway – Galway, Ireland |
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| | Karolinska Institutet – Flemingsberg, Sweden |
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| | CRUK Manchester Institute – Manchester, England, United Kingdom |
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| | Stanford Medicine – Stanford, California, United States |
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| | Darmstadt University of Technology – Darmstadt, Germany |
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