Intact Fibroblast Growth Factor 23 Regulates Chronic Kidney Disease–Induced Myocardial Fibrosis by Activating the Sonic Hedgehog Signaling Pathway

Researchers found that Gli‐1 and Smoothened in the Sonic Hedgehog signaling pathway were activated and that collagen‐1 and collagen‐3, which constituted the fibrotic index, were expressed in chronic kidney disease myocardial tissue.