 | | Vol. 14.00 – 5 January, 2023 |
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| Scientists reported the safety and feasibility of an intravascularly infused ECM as a biomaterial for the repair of tissue in animal models of acute myocardial infarction, traumatic brain injury, and pulmonary arterial hypertension.
[Nature Biomedical Engineering] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers found that fibroblast activation protein (Fap) was significantly elevated in osteoarthritic synovium, while the genetic deletion of Fap significantly ameliorated posttraumatic osteoarthritis in mice.
[Bone Research] |
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| The authors investigated the effect of viscoelasticity on migration and fusion behavior of MSC spheroids using hydrogels with a similar elasticity but different stress relaxation profiles.
[Bioengineering & Translational Medicine] |
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| Investigators identified a mechanosensing feedback mechanism between the ECM and cytoskeletal network that regulated mitochondrial function under healthy conditions.
[Communications Biology] |
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| Researchers identified Epstein-Barr virus (EBV) expression in the tumor immune microenvironment (TIM) in colorectal cancer tissue and investigated the effects of EBV on TIM composition and clinical outcomes.
[iScience] |
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| Scientists investigated the osteoregenerative capacity of collagen/chitosan/hydroxyapatite scaffolds in rats with hormone deficiency caused by experimental bilateral ovariectomy.
[Scientific Reports] |
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| Investigators developed an injectable pig cartilage-derived decellularized ECM hydrogels for the repair of cartilage defects, which showed sound biocompatibility and immunomodulatory capacity both in vitro and in vivo.
[Npj Regenerative Medicine] |
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| The authors investigated the spatial correlation between the cells and the ECM in the growth plate matrix and basement membrane and investigated the expression of integrins—ECM receptors—in the cells.
[Journal Of Anatomy] |
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| A bi-functional EBP-PR1P peptide was designed and bridged vascular endothelial growth factor to injectable cardiac extracellular matrix.
[Journal Of Biomedical Materials Research Part A] |
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| Scientists describe the behaviors of highly heterogeneous and plastic macrophage subpopulations which affect tissue regeneration, by reviewing the latest literature that explored the immune microenvironment mediated by ECM scaffolds.
[Biomedical Materials] |
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| UBC faculty of medicine’s Drs. Allen Eaves and Paula Gordon were among the UBC community members who have been appointed to the Order of Canada.
[UBC Faculty of Medicine] |
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| March 6 – 8, 2023
Paris, France |
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| | Dankook University – Seoul, South Korea |
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| | US FDA – Silver Spring, Maryland, United States |
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| | The University of British Columbia – Vancouver, British Columbia, Canada |
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| | Albert Einstein College of Medicine – Bronx, New York, United States |
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| | University of Nebraska Medical Center – Omaha, Nebraska, United States |
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