 | | Vol. 14.03 – 26 January, 2023 |
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Scientists proposed a novel ECM-inspired injectable hydrogel for adipose-derived stem cell encapsulation and rheumatoid arthritis treatment.
[Advanced Science] |
|  | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers reported a semiconducting polymer-based ECM nanoremodele for activatable cancer photo-immunotherapy, which has photodynamic antitumor activity, and cancer-specific inhibition of collagen-crosslinking enzymes.
[Angewandte Chemie-International Edition] |
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| Scientists developed a novel model of accelerated tendon ECM aging via depletion of Scleraxis-lineage cells in young mice (Scx-DTR). Scx-DTR recapitulated many aspects of tendon aging including comparable declines in cellularity, alterations in ECM structure, organization, and composition.
[Elife] |
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| The authors showed that the disturbance of mechanical cue homeostasis occurs after uterine injury and identified YAP as a sensor of biophysical forces that drive endometrial regeneration.
[Cell Communication and Signaling] |
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| Researchers found that the expression of miR-99b increased with increasing hydrogel stiffness and that miR-99b regulated the proliferation and differentiation of BMSCs seeded on the surface of substrates with different stiffnesses.
[APL Bioengineering] |
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| The authors showed that cells previously primed on stiff matrices, compared to soft, generated higher forces to remodel collagen fibers, and promoted invasion.
[Molecular Biology of the Cell] |
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| Scientists created photocontrolled stiffness-tunable DNA nanotubes which could undergo reversible changes in their conformation upon ultraviolet and VIS irradiation.
[Nanoscale] |
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| Researchers showed that pancreatic islets could become incorporated and function in a non-thermal irreversible electroporation-generated ECM niche, albeit at a low success rate.
[Radiology and Oncology] |
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| Investigators reported a novel kind of bone ECM-inspired biomineralization chitin whisker liquid crystal (LC) hydrogels. Photocurable chitin whisker LC hydrogels with bone ECM-like chiral nematic LC state and viscoelasticity were created.
[International Journal of Biological Macromolecules] |
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| Scientists showed that bardoxolone methyl inhibited nuclear factor-κB ligand-induced osteoclast formation and ECM degradation by activating the Nrf2/HO-1 signaling pathways and inhibiting NF-κB pathway activation and excess reactive oxygen species production.
[Heliyon] |
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| Investigators introduce the hallmarks of the tumor microenvironment (TME) and discuss biomaterials and nanomedicine technologies that can regulate the TME of solid tumors to improve the efficacy of different types of immunotherapy.
[Nature Reviews Bioengineering] |
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| Aston University announced that they are working with a start-up company, Isterian Biotech, part of Cambrian BioPharma, to develop novel drugs to treat fibrotic diseases such as lung disease.
[Aston University] |
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| April 23 – 28, 2023
Cancun, Mexico |
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| | National University of Ireland Galway – Galway, Ireland |
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| | The Ottawa Hospital – Ottawa, Ontario, Canada |
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| | European Molecular Biology Laboratory – Barcelona, Spain |
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| | BioMed X Institute – New Haven, Connecticut, United States |
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| | Aspect Biosystems – Vancouver, British Columbia, Canada |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
