 | | Vol. 14.07 – 23 February, 2023 |
| |
|
|
| Researchers demonstrated that a microgel-based biphasic bioink could be used as both an excellent bioink and a suspension medium that supports embedded 3D printing due to its shear-thinning and self-healing behavior.
[Advanced Materials] |
|  |
|
|
| PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Investigators introduced a fully enzymatic strategy for hydrogel degradation that affords spatiotemporal control over cell release while maintaining cytocompatibility.
[Advanced Materials] |
|
|
|
| The authors delineated a molecular pathway that links stiff ECM to activation of Akt, which in turn promoted GTP loading to Rab8 that drove’ exosome secretion.
[Nature Cell Biology] |
|
|
|
| TrkB suppressed TGFβ-stimulated proliferation and activation of hepatic stellate cells (HSCs) and in 3D liver spheroids and significantly repressed TGF-β/SMAD signaling pathway either in HSCs or in hepatocytes.
[Hepatology] |
|
|
|
| Investigators developed a novel approach to mitigate this scattering-induced deterioration of bioprinting resolution. The inclusion of iodixanol in the bioink enables a 10-fold reduction in light scattering and a substantial improvement in fabrication resolution for bioinks with an high cell density.
[Science Advances] |
|
|
|
| Scientists presented a thermomechanical approach to replicate the combinational properties of soft tissues in protein-based photocrosslinkable hydrogels.
[Proceedings Of The National Academy Of Sciences Of The United States Of America] |
|
|
|
| Single-cell transcriptome analysis of hepatic CD11b+ cells, main producers of matrix metalloproteinases, revealed a prominent cluster of restorative Tlr4-expressing Ly6c2-low myeloid cells.
[iScience] |
|
|
|
| Across tumor types, epithelial-to-mesenchymal transition-related gene expression was strongly associated with expression of stroma-related genes.
[Scientific Reports] |
|
|
|
| Scientists established patient-derived spheroids and patient-derived organoids from patient-derived cancer cells isolated from the malignant pleural effusion in eight patients.
[Heliyon] |
|
|
|
|
| The authors unify the follicular and non-follicular, non-endothelial stroma of tumours under the ‘peripheral adaptive immune mesenchyme’ framework and position subsets of cancer-associated fibroblasts as direct positive regulators of the adaptive immune system.
[Nature Reviews Cancer] |
|
|
|
| The ECM, long considered an inert scaffold, can now be seen as a highly dynamic partner to the immune system.Investigators aim to highlight the absolute interdependence of these systems with consequences for therapy.
[Science] |
|
|
|
| Among the many cellular organelles and cell surface receptors that sense morphogen and ECM signals, the primary cilia and integrin receptors are some of the most important mediators of extracellular signals.
[Frontiers In Cell And Developmental Biology] |
|
|
|
|
| The European Association for Cancer Research announced that the winner of the 2023 Pezcoller-Marina Larcher Fogazzaro-EACR Women in Cancer Research Award is Dr. Johanna Joyce, whose research expertise is in cancer biology, immunology, and the tumour microenvironment.
[European Association for Cancer Research] |
|
|
|
| “I have a dream; the synthesis of an artificial extracellular matrix.” The opening line of Patricia Dankers’ presentation pitch for a prestigious NWO Vici grant worth 1.5 million euros to synthesize an artificial version of the material that surrounds cells in the human body. That dream is on its way to reality.
[Eindhoven] |
|
|
|
| ChitogenX, Inc. said it has obtained, in partnership with Polytechnique Montréal, a $3,472,000 grant from The Natural Sciences and Engineering Research Council of Canada and Prima Québec.
[ChitogenX, Inc. (Proactive Investors)] |
|
|
|
| | April 20 – 21, 2023
Sheffield, England, United Kingdom |
|
|
|
|
|
| | The University of Manchester – Mandarin, England, United Kingdom |
|
|
|
| | Penn Medicine – Philadelphia, Pennsylvania, United States |
|
|
|
| | University Medical Center Utrecht – Utrecht, Netherlands |
|
|
|
| | Loughborough University – Leicestershire, England, United Kingdom |
|
|
|
| | Khalifa University – Abu Dhabi, United Arab Emirates |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
