 | | Vol. 14.31 – 13 July, 2023 |
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| Researchers used a combination of microsurgical, immunofluorescent, and transcriptomic approaches to compare decellularized tracheal grafts neotissue with the native airway and surgical controls.
[NPJ Regenerative Medicine] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The authors identified Spock1 as a candidate neuronal signal for regulating blood-brain barrier (BBB) permeability in zebrafish and mice. Mosaic genetic analysis shows that neuronally expressed Spock1 is cell non-autonomously required for a functional BBB.
[Developmental Cell] |
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| Scientists examined ECM modifications to elucidate the mechanism underlying carcinoma ex pleomorphic adenoma tumorigenesis. RNA-sequencing and bioinformatic analysis of organoids showed that differentially expressed genes are highly enriched in ECM-associated terms.
[Cell & Bioscience] |
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| Investigators identified a bioactive peptide domain of COL5, WWASKS, through bioinformatic analysis of decellularized pancreatic ECM-derived collagens. RNA-sequencing suggests that WWASKS induces the formation of pancreatic endocrine progenitors while suppressing the development of other types of organs.
[Journal Of Tissue Engineering] |
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| A nanofibrous membrane wound dressing material based on recombinant human collagen type III crosslinked by EDC/NHS, which incorporated multiple Gly–Glu–Lys and Gly–Leu–Ser–Gly–Glu–Arg integrin receptors, has been developed utilizing green electrospinning technology.
[Journal Of Materials Chemistry B] |
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| The changing collagen composition in tumors along with their impact on patient outcomes and possible biomarkers remains largely unknown. The RNA expression of the 43 collagen genes from solid tumors in The Cancer Genome Atlas (TCGA) was clustered to classify tumors.
[NPJ Genomic Medicine] |
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| Investigators demonstrated that acupuncture treatment reduced the ulcerative colitis symptoms, disease activity index score, and histological colitis score and increased body weight, colon length, and the number of intestinal goblet cells.
[Experimental Biology And Medicine] |
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| Researchers proposed a phase-transition model to account for the rapid development of ordered fibrils in embryonic tendon, reducing reliance on active cellular processes.
[Biophysical Journal] |
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| A sheep lung was decellularized to achieve decellularized ECM (dECM) scaffolds and hydrogels. Afterwards, the obtained dECM scaffold was evaluated for collagen and glycosaminoglycan contents, DNA quantification, and its ultrastructure.
[Cell Journal] |
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| By combining the dynamic properties of the self-assembling peptides conjugated with full-length proteins, peptide-based supramolecular materials enable neuronal migration and regeneration of injured neural tissue.
[Chemical Communications] |
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| Swiss medical technology company, Regen Lab, announced a new collaboration agreement with the Moroccan Ministries of Health and Industry aiming to boost regenerative medicine in Morocco and Africa.
[Morocco World News] |
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| October 1 – 4, 2023
Toronto, Ontario, Canada |
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| | University College Dublin – Dublin, Ireland |
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| | Maastritch University – Maastricht, Netherlands |
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| | National University of Singapore – Singapore, Singapore |
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| | Albert Einstein College of Medicine – New York City, New York, United States |
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| | Centre for Oncology and Immunology – Hong Kong, Hong Kong |
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