 | | Vol. 14.32 – 10 August, 2023 |
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| The Gelation of Uniform Interfacial Diffusant in Embedded 3D Printing approach for constructing perfusable networks of interconnected channels with precise control over branching geometries and vessel sizes was presented.
[Advanced Functional Materials] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists presented a reliable, and simply reproducible process for constructing user-controlled long rounded ECM embedded vascular microlumens on-chip for endothelization and co-culture with stromal cells obtained from human lung.
[Advanced Functional Materials] |
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| The authors generated αPD-1 resistant variants of the murine HNSCC model MEER. While entirely αPD-1 resistant, these tumors regressed after single dose of oncolytic vaccinia virus .
[Journal Of Experimental Medicine] |
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| A human endogenous retrovirus (HERV) sequence upstream of the calbindin gene, CALB1, promoted the transcription of an HERVH-CALB1 transcript through a splice event at the third CALB1 exon in a process known as protein exaptation.
[Cancer Research] |
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| The authors showed that C. elegans males recognized conspecific and reproductive mates through short-range cues, and that the attractiveness of potential mates depends on the sex and developmental stages of the hypodermis.
[Current Biology] |
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| Scientists presented a computational method to systematically infer and quantify long-range cell-cell force transmission through the ECM.
[Communications Biology] |
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| Researchers demonstrated that basonuclin-2, a mesenchymal-expressed gene, that is, strongly associated with cancer and developmental defects across genome-wide association studies, was a novel regulator of ECM composition and degradation.
[Life Science Alliance] |
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| The authors established collagen-induced arthritis model in wild-type and Tau-/- mice to compare the clinical score and arthritis incidence. Micro-CT analysis was used to evaluate bone erosion of ankle joints.
[Arthritis Research & Therapy] |
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| Researchers collected synovial tissues of RA patients and FLS-RA and cultured FLS for detection of expression of SMAD2. ASC, NLRP3, cleaved-caspase-1, and GSDMD-N were detected by Western blot after overexpression of SMAD2.
[Arthritis Research & Therapy] |
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This retrospective study assessed the complications and efficacy of basic fibroblast growth factor-impregnated collagen gelatin sponge (bFGF-CGS) to reduce fistula formation. Patients who underwent primary palatoplasty with bFGF-CGS were included.
[Regenerative Therapy] |
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| Investigators describe mechanisms of action for anti-cancer therapies and mechanotransduction programs that regulate cellular processes, including cell proliferation, apoptosis, survival and phenotype switching.
[Trends In Cancer] |
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| Scientists highlight approaches to examine ECM mechanics at tissue and cellular levels, focusing on how mechanical interactions between cells and the ECM regulate vascular phenotype, especially under certain pathological conditions.
[Nature Cardiovascular Research] |
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| Researchers at City of Hope were awarded $32.3 million from the California Institute for Regenerative Medicine (CIRM) to support three novel Phase I clinical trials evaluating innovative cell and gene therapy treatments for patients with HIV, acute myeloid leukemia and severe aplastic anemia.
[City of Hope] |
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October 19 – 22, 2023
Minneapolis, Minnesota, United States |
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| | The University of Copenhagen – Copenhagen, Denmark |
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| | Center for Excellence in Molecular Cell Science – Shanghai, China |
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| | National University of Singapore – Singapore, Singapore |
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| | University of Maryland – College Park, Maryland, United States |
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| | IRB Barcelona – Barcelona, Spain |
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