 | | Vol. 14.33 – 27 July, 2023 |
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| Researchers performed scRNAseq of 13 fresh full thickness Crohn’s disease (CD) resections containing non-involved, inflamed non-strictured, and strictured segments as well as seven normal non-CD bowel segments.
[Gastroenterology] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators attempted to fabricate 3D-printing titanium grid scaffolds, which possess sufficient pores and basic biomechanical strength to facilitate osteogenesis in order to accomplish bone fusion in mandibular segmental bone defects.
[NPJ Regenerative Medicine] |
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| Scientists developed models of conditional depletion of SF-1 or LRH-1 from prenatal ovaries. Depletion of SF-1, but not LRH-1, resulted in dramatically smaller ovaries and fewer primordial follicles.
[Proceedings Of The National Academy Of Sciences Of The United States Of America] |
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| The authors attempted to determine in older adults if metformin monotherapy during bed rest could reduce muscle fibrosis and cellular senescence/senescent associated secretory phenotype during the re-ambulation period.
[Aging Cell] |
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| Scientists reported that cutaneous squamous cell carcinoma cells (cSCC) secreted an increased number of extracellular vesicles (EVs) relative to normal human epidermal keratinocytes and that interfering with the capacity of cSCC to secrete EVs inhibited tumor growth in vivo in a xenograft model of human cSCC.
[Cell Death Discovery] |
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| Investigators prepared a chitosan-collagen hydrogel nerve conduit (CCN) consisting of an outer layer of chitosan hydrogel and an inner layer of collagen hydrogel to encapsulate the intended cells.
[Scientific Reports] |
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| The authors previously reported a heparan sulfate variant with enhanced affinity for bone morphogenetic protein-2, termed HS3, that enhanced periodontal tissue regeneration in a rodent model. They thought to transition this work closer to the clinic.
[Scientific Reports] |
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| As ECM was recognized as a vital component in directing cellular function and differentiation, scientists sought to derive hydrogels from decellularized human lung alveolar-enriched ECM to provide an ex vivo model to characterize the role of physiologically relevant ECM on induced pluripotent stem cells phenotype.
[Scientific Reports] |
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| Conducting a systemic review, scientists concluded that there is currently insufficient evidence to determine the effectiveness of hyaluronic acid dressings in the healing of pressure ulcers or foot ulcers in people with diabetes.
[Cochrane Library] |
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| The American Federation for Aging Research has recognized the exemplary contributions of Dr. Ming Xu, assistant professor of the University of Connecticut (UConn) Center on Aging and the Department of Genetics & Genome Sciences at UConn School of Medicine.
[University of Connecticut] |
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| A new international consortium called HU3DINKS is rallying behind a single mission: to develop advanced human tissue-based bioinks for 3D bioprinting.
[3DPrint.com] |
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| October 5 – 7, 2023
Boston, Massachusetts, United States |
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| | Centre for Oncology and Immunology – Hong Kong, Hong Kong |
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| | Washington University – St. Louis, Missouri, United States |
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| | TU Dresden – Dresden, Germany |
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| | University College Dublin – Dublin, Ireland |
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| | Maastritch University – Maastricht, Netherlands |
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