 | | Vol. 14.43 – 26 October, 2023 |
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| Muscle injury recruited natural killer cells that produced Xcl1 when stimulated with fragmented extracellular matrix.
[Nature Materials] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists proposed that the specific protein assemblies within the cell-derived ECM, whose morphological features are widely tailorable, and could be employed as versatile biotemplates.
[Advanced Science] |
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| Inspired by the bone tissue composition, a novel pearl powder hybrid fish gelatin methacrylate hydrogel scaffold loaded with vascular endothelial growth factor for bone regeneration was presented.
[Advanced Science] |
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| The hybrid cell membrane (MM) loaded small interfering RNA-polyvinylimide (siRP) was synthesized as siRNA@MMs to coat on polylactone electrospun fibers for mimicking the natural bone matrix.
[Small] |
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| To recapitulate the remodelability of the neural ECM, scientists developed a family of protein-engineered hydrogels that exhibited tunable stress relaxation rates.
[Science Advances] |
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| Genetic manipulation and single-cell transcriptomics showed that the receptor signals activation of an “extracellular matrix remodeling” transcriptional program in a macrophage subset, which served as a key regulator of matrix composition and turnover.
[Developmental Cell] |
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| The viral protein VP33L was identified as a novel component of virus-mock basement membrane (VMBM), and the way it participates in VMBM assembly was investigated.
[Journal Of Virology] |
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| Osteoarthritis (OA) cartilage was obtained from OA knees at macroscopically preserved areas and degenerated areas, while control cartilage was collected from non-arthritic knees. Released proteins were obtained by repeatedly applying compressive loading, which simulated loading on cartilage in vivo.
[Scientific Reports] |
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Researchers presented proof-of-concept to use machine learning tools to predict the role of the interactions between cells and the ECM in the self-organization of cell-laden hydrogels grown in tethered molds.
[Physical Biology] |
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| The authors review the current literature about ECM remodeling by matrix metalloproteinase in intestinal fibrosis and their potential role as biomarkers for disease progression or druggable targets.
[Journal Of Crohns & Colitis] |
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| Keep working on it. That’s the reaction of US science watchdog groups to the first attempts by federal health agencies to flesh out a promise by President Joe Biden to restore trust in government by ensuring that government scientists are free to do their jobs without political meddling.
[ScienceInsider] |
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| November 26 – 29, 2023
Buxted Park, England, United Kingdom |
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| | Cedars-Sinai – Los Angeles, California, United States |
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| | University of Liverpool – Liverpool, England, United Kingdom |
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| | EPFL – Lausanne, Switzerland |
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| | Washington University in St. Louis – Saint Louis, Missouri, United States |
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| | ShanghaiTech University – Shanghai, China |
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