 | | Vol. 14.49 – 7 December, 2023 |
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| Investigators reported a facile and universal metabolic tagging technology that could install unique chemical tags onto extracellular vesicles (EVs). The surface chemical tags enabled the conjugation of molecules via efficient click chemistry, for the tracking and targeted modulation of EVs.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers developed a molecular tension sensor that embeds into the F-actin cytoskeleton. Using this sensor, they measured tension within stress fibers and cortical actin, as the cell was subject to uniaxial stretch.
[Nature Communications] |
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| An injectable hydrogel microsphere system focusing on the hypoxic inflamed joint was prepared with methacrylate-modified sulfonated azocalixarene, methacrylated hyaluronic acid, and dithiol-terminated matrix metalloproteinase 13 sensitive peptide via a microfluidic device and photo crosslinking technique.
[Small] |
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| Scientists focused on harnessing nature-inspired self-assembly of ECM-like coatings on Ti alloy with a combination of jellyfish-derived collagen and hyaluronic acid using our customized automated hybrid layer-by-layer apparatus.
[ACS Applied Materials & Interfaces] |
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| Investigators found the C-type lectins including Colec10 and Colec11 were not produced by hepatocytes but predominantly produced by hepatic stellate cells, especially quiescent ones in the mice livers. In vitro overexpression of COLEC10 in LX-2 cells promoted the mRNA expression of ECM components.
[Cell Death & Disease] |
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| Researchers determined whether tanshinone IIA could directly act on the skin fibroblasts of scleroderma and look into its underlying anti-fibrotic mechanisms.
[Stem Cells] |
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| Scientists investigated the suitability of poly(carbonate-urea-urethane) as polymers for the manufacturing of nonwoven mats by electrospinning, able to closely mimic the fibrous structure of the extracellular matrix.
[ACS Biomaterials Science & Engineering] |
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| Ramelteon partially abrogated TGF-β1-induced pulmonary fibrosis and reduced fibroblast proliferation, extracellular matrix deposition, and differentiation into myofibroblasts. In vivo experiments, ramelteon attenuated bleomycin-induced pulmonary fibrosis and collagen deposition.
[Naunyn-Schmiedebergs Archives Of Pharmacology] |
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| Investigators collected small extracellular vesicles from breast cancer tissues, paired normal tissues, corresponding plasma, and tumor organoids to characterize their transcriptomic and proteomic profiles.
[MedComm] |
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| The authors review the role of different compounds with antioxidant activity in the induction or inhibition of TGF-β/SMAD signaling pathway, with regard to different fibrotic conditions such as gastro-intestinal fibrosis, cardiac fibrosis, pulmonary fibrosis, skin fibrosis, renal fibrosis, and also some rare cases of fibrosis.
[Journal Of Cellular And Molecular Medicine] |
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| Sanara MedTech Inc. announced that the Journal of Surgery has published a retrospective study on CellerateRX® Surgical Powder titled “Activated Collagen Powder Significantly Reduces Surgical Site Infections in Patients Undergoing Elective Surgery”.
[Sanara MedTech, Inc.] |
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| January 28 – February 2, 2024
Galveston, Texas, United States |
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| | Utrecht University – Utrecht, Netherlands |
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| | University of Montpellier – Montpellier, France |
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| | The Hong Kong University of Science and Technology – Guangzhou, China |
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| | University of Washington – Medical lake, Washington, United States |
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| | Albert-Ludwigs-University Freiburg – Freiburg im Breisgau, Germany |
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