 | | Vol. 15.00 – 4 January, 2024 |
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| Fiber alignment gradients in biopsy samples were characterized and recreated using a new microfluidic biofabrication technique to achieve tunable sub-millimeter to millimeter scale gradients.
[Advanced Functional Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| To investigate the Murphy Roths Large (MRL) ECM, cellular components were removed from dystrophic muscle sections to generate decellularized myoscaffolds. Decellularized myoscaffolds from dystrophic mice in the protective MRL strain had less deposition of collagen and matrix-bound TGF-β1 and TGF-β3.
[JCI Insight] |
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| Scientists introduced a fully-implantable wireless-powered tactile sensory system embedded in artificial skin, with stable operation, to restore permanently damaged tactile function and promote wound healing for regenerating severely damaged skin.
[Nature Communications] |
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| Researchers presented a human apical-out airway organoid using a biochemically defined hybrid hydrogel system. The expression and activity of ECM-degrading enzymes, and matrix metalloproteinases increase during organoid differentiation.
[Nature Communications] |
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| Based on harvesting the cell sheet via a photothermal response strategy, a fibronectin-attached cell sheet (FACS) was prepared to enhance its wound repair capability. In vivo wound healing experiment confirmed the reparative efficacy of FACS.
[Advanced Science] |
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| Investigators demonstrated that the laminin-augmented porcine brain-decellularized ECM was xenogeneic factor-depleted as well as favorable for the regulation of human neurons, astrocytes, and microglia.
[Small] |
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| Scientists analyzed cultured mouse periodontal ligament cell (PDLC)-derived ECM and compared it to mouse PDL tissue. Proteomic analysis revealed that the cultured PDLC-derived ECM had lower proportions of fibrillar collagens with increased levels of glycoprotein, corresponding to an immature ECM status.
[Scientific Reports] |
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| Researchers investigated the effect of organized collagen matrix fibers on leader cell mechanics and demonstrated that leader cells protruded along aligned fibers resulting in an elongated phenotype of the entire cluster.
[PLOS One] |
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| Since the connection between cells and matrix was provided by transmembrane integrin receptors, scientists aimed at studying the dynamics of signaling pathways associated with integrins on an in vitro model of wound healing using human skin fibroblasts.
[Applied Biochemistry And Biotechnology] |
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| The authors discuss the complex process of ECM regulation in trabecula meshwork (TM) and explore promising therapeutic targets. The role of transforming growth factor-β as a central player in ECM deposition in TM is discussed.
[Expert Opinion On Therapeutic Targets] |
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| Sanara MedTech Inc. announced that it has signed an exclusive license agreement with Tufts University to develop and commercialize patented technology covering 18 unique collagen peptides.
[Sanara Medtech, Inc.] |
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| February 14 – 18, 2024
Cancun, Mexico |
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| | UiT The Arctic University of Norway – Tromsø, Norway |
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| | H. Lee Moffitt Cancer Center & Research Institute – Tampa, Florida, United States |
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| | University of Michigan – Ann Arbor, Michigan, United States |
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| | Utrecht University – Utrecht, Netherlands |
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| | Ottawa Hospital Research Institute – Ottawa, Ontario, Canada |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
