 | | Vol. 15.01 – 11 January, 2024 |
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| Fiber alignment gradients in biopsy samples were characterized and recreated using a new microfluidic biofabrication technique to achieve tunable sub-millimeter to millimeter scale gradients, representing the first successful engineering of continuous alignment gradients in soft, natural biomaterials.
[Advanced Functional Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| To investigate the Murphy Roths Large (MRL) ECM, cellular components were removed from dystrophic muscle sections to generate decellularized myoscaffolds. Decellularized myoscaffolds in the protective MRL strain had significantly less deposition of collagen and matrix-bound TGF-β1 and TGF-β3.
[JCI Insight] |
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| Scientists introduced a fully-implantable wireless-powered tactile sensory system embedded in artificial skin, with stable operation, to restore permanently damaged tactile function and promote wound healing for regenerating severely damaged skin.
[Nature Communications] |
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| The expression and activity of ECM-degrading enzymes and matrix metalloproteinases increased during organoid differentiation, where inhibition of MMPs significantly suppresses the normal ciliation, resulting in increased goblet cell proportion.
[Nature Communications] |
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| Based on harvesting the cell sheet via a photothermal response strategy, a fibronectin-attached cell sheet (FACS) was prepared to enhance its wound repair capability. In vivo wound healing experiment confirmed the reparative efficacy of FACS.
[Advanced Science] |
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| Investigators demonstrated that the laminin-augmented porcine brain-decellularized ECM was xenogeneic factor-depleted as well as favorable for the regulation of human neurons, astrocytes, and microglia.
[Small] |
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| Researchers systematically analyzed cultured mouse periodontal ligament cell (PDLC)-derived ECM and compared it to mouse PDL tissue as a reference. Proteomic analysis revealed that, compared to PDL tissue, the cultured PDLC-derived ECM had a lower proportion of fibrillar collagens.
[Scientific Reports] |
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| To comprehend the development of fibrosis and find effective biomarkers for its diagnosis, researchers prepared streptozotocin-induced long-term diabetic Sprague-Dawley rats exhibiting a type 1 diabetes phenotype and bladder fibrosis in histology detection.
[Scientific Reports] |
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| Since the connection between cells and matrix was provided by transmembrane integrin receptors, scientists aimed at studying the dynamics of signaling pathways associated with integrins on an in vitro model of wound healing using human skin fibroblasts.
[Applied Biochemistry And Biotechnology] |
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| The authors discuss the complex process of ECM regulation in trabecula meshwork (TM) and explore promising therapeutic targets. The role of transforming growthfFactor-β as a central player in ECM deposition in TM is discussed.
[Expert Opinion On Therapeutic Targets] |
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| Sanara MedTech Inc. announced that it has signed an exclusive license agreement with Tufts University to develop and commercialize patented technology covering 18 unique collagen peptides.
[Sanara Medtech, Inc.] |
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| February 21 – 24, 2024
San Antonio, Texas, United States |
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| | City of Hope – Duarte, California, United States |
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| | UiT The Arctic University of Norway – Tromsø, Norway |
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| | H. Lee Moffitt Cancer Center & Research Institute – Tampa, Florida, United States |
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| | University of Michigan – Ann Arbor, Michigan, United States |
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| | University of California, San Francisco – San Francisco, California, United States |
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Cancer Stem Cell News
Cell Therapy News
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Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
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Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
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Neural Cell News
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