 | | Vol. 15.07 – 22 February, 2024 |
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| A hierarchical composite scaffold with deferoxamine (DFO) delivery system was developed, focusing on vascularized bone regeneration. The hierarchical structure imitated the microstructure of natural bone and interacted with the local ECM, facilitating cell adhesion and proliferation.
[Advanced Healthcare Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| An innovative triple cross-linked oxidized hyaluronic acid-dopamine- polyacrylamide composite hydrogel, modified with collagen mimetic peptide and supplied with transforming growth factor beta 1, was developed for annulus fibrosus regeneration.
[Acta Biomaterialia] |
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| Researchers used a collagen peptide sensor to visualize collagen formation and remodeling during wound healing in mice and humans. They showed that the probe bound selectively to sites of collagen formation and remodeling at different stages of healing.
[Matrix Biology] |
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| Scientists reported the generation and characterization of hydrogels derived from decellularized extracellular matrix prepared from WT or thrombospondin (TSP)-2 null muscle tissue.
[Matrix Biology] |
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| Scientists highlighted the significance of poplar MYC2s and terpenes in mutualistic symbiosis by controlling root fungal colonization. They identified poplar genes in which direct or indirect control by MYC2 is required for ECM establishment.
[New Phytologist] |
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| Researchers investigated the electrophysiological properties, synaptic activity, and gene expression differences in dopaminergic neurons derived from iPSCs of healthy controls, sporadic Parkinson’s disease (PD) patients, and PD patients with E326K-GBA1 mutations.
[npj Parkinson’s Disease] |
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| Investigators proposed that MSC-extracellular vesicles (EVs) could be combined with histone deacetylase 7-derived 7-amino-acid peptide (7A) to greatly promote diabetic wound healing. The combination of EVs and 7A significantly improved the migration and proliferation of skin fibroblasts.
[Biomaterials Science] |
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| A combined method was proposed to easily functionalize collagen surface films, tailoring morphological properties. Oxygen nonthermal plasma treatment and glyco-conjugation with chondroitin sulfate are used to modify surface properties.
[Nanomedicine] |
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| Human nipple–areolar complex were harvested from cadaveric donors and decellularized using sequential detergent baths. Cellular clearance and ECM preservation were analyzed by histology, as well as by DNA, ECM proteins, growth factors, and residual sodium dodecyl sulfate quantification.
[Frontiers In Bioengineering And Biotechnology] |
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| Lead researcher Dr. Elena Rainero, from the University of Sheffield’s School of Biosciences, and her team investigated how tumors continue to grow – despite the lack of nutrients in the ECM – and how the tumor cells supply themselves with the raw materials to support their growth.
[Scitechdaily] |
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| March 11 – 13, 2024
Lisbon, Portugal |
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| | Center for Colloid and Surface Science – Florence, Italy |
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| | Foundation for Liver Research – London, England, United Kingdom |
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| | University of Michigan – Ann Arbor, Michigan, United States |
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| | Trinity University – San Antonio, Texas, United States |
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| | Universitätsklinikum Ulm – Ulm, Germany |
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