| Vol. 14.22 – 27 April, 2023 |
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| Scientists presented a novel stem cell spheroid-loaded microneedle patch using microfluidic templating technology. By leveraging the precise fluid manipulation capabilities of the microfluidic template, stem cell spheroids with uniform size can be generated in situ. [Advanced Materials] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Gglycopolymer-based supramolecular hydrogels were synthesized to direct adaptive glia repair after central vervous system (CNS) injury. [Advanced Materials] |
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| In vitro, Mn3O4 nanozymes were confirmed to reprogram both the imbalance of metabolism in chondrocytes and the uncontrolled inflammatory response stimulated by hydrogen peroxide. [Advanced Science] |
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| Investigators designed hybrid drug-loaded nanoliposomes by co-loading the chemotherapeutic drug temozolomide and nitric oxide prodrug JS-K with sphingosine-1-phosphate molecules on the surface. [Advanced Science] |
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| An in situ nanovaccine strategy targeting lymph nodes (LNs) to induce powerful antitumor immune responses by converting the primary tumor into whole-cell antigens and then delivering these antigens and nanoadjuvants simultaneously to LNs was proposed. [Small] |
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| To investigate why lesions within an osteoarthritis (OA) environment fail to heal, a heterogeneous cell population was isolated from the synovial fluid of OA patients. [Science Advances] |
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| Investigators examined the morphogenetic function of an ECM before reaching homeostatic equilibrium by analyzing de novo ECM assembly during Drosophila ventral nerve cord condensation. [Developmental Cell] |
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| Scientists described a strategy to develop phage-display libraries of nanobodies against ECM proteins expressed in human metastases, using as immunogens entire ECM-enriched preparations from triple-negative breast cancer and colorectal carcinoma metastases to different organs as immunogens. [Cancer Research] |
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| Researchers described a strategy to develop phage-display libraries of nanobodies against ECM proteins expressed in human metastases, using as immunogens entire ECM-enriched preparations from triple-negative breast cancer and colorectal carcinoma metastases to different organs as immunogens. [Cancer Research] |
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| The authors focused on how the corneal epithelial stem cell (SC) model in which the SC niche, known as the limbus, was spatially segregated from the differentiation compartment. [Cell Death & Differentiation] |
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| Investigators found that vascular smooth muscle cells-specific Prdm16 knockout mice already showed extensive changes in the expression of genes associated with ECM remodeling and inflammation in the abdominal aorta under normal housing conditions without any pathological stimuli. [JCI Insight] |
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| The authors highlight challenges in recapitulating the biological complexity seen in bone and how synergistic application of dynamic hydrogels and innovative bioprinting pipelines could address these challenges to achieve bone models. [Advanced Materials] |
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| Despite their abundance throughout the body, adipocytes are often ignored for their contributions within the tumor microenvironment (TME). However, their role in fueling cancer is becoming increasingly apparent as interest in the TME has seen remarkable advances in recent years. [Cancer Research] |
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| Scientists review how dermal aging involves a feed‐forward process that reinforces the aged dermal fibroblast phenotype and promotes age‐related dermal ECM deterioration, and discuss the expression of the aged dermal fibroblast phenotype. [Journal Of Cell Communication And Signaling] |
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| The Icahn School of Medicine at Mount Sinai announced the creation of the Institute for Regenerative Medicine to foster innovative research into new pathways to cure a host of diseases from leukemia to Alzheimer’s disease, breast cancer, and airway diseases. [Icahn School of Medicine at Mount Sinai]] |
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| May 28 – 31, 2023 Killarney, Ireland |
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| Wake Forest University – Winston Salem, North Carolina, United States |
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| University of Gothenburg – Gothenburg, Sweden |
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| University of Melbourne – Melbourne, Australia |
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| University Medical Center Groningen – Groningen, Netherlands |
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