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| Scientists found that tumor cells may achieve a “tumor microenvironment (TME) remodeling pattern” through an “immune pressure-sensing model”, in which they could choose to reshape the TME into a barrier environment or a cold environment according to the immune pressure.
[Leukemia] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The response of primary and metastatic lesions to first-line anti-PD-1 monotherapy was evaluated by radiology. Cells from primary lesions of patients with microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer were analyzed using scRNA-seq.
[BMC Medicine] |
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| The authors reported a modular handheld bioprinter that deposits a variety of bioinks in situ with exquisite control over their physical and chemical properties. Combined stereolithography 3D printing and microfluidic technologies allowed us to develop a novel low-priced handheld bioprinter.
[Biofabrication] |
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| Assisted by the surface modification, MP3/ACPP/AE105@NPs demonstrated excellent cellular uptake of the drugs in in vitro experiments, thereby enhancing the therapeutic utility of the loaded metal complex.
[Npg Asia Materials] |
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| Scientists found that tumor cells may achieve a “tumor microenvironment remodeling pattern” through an “immune pressure-sensing model”, in which they could choose to reshape the TME into a barrier environment or a cold environment according to the immune pressure.
[Cell Reports] |
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| Investigators evaluated the structures and functions of the jellyfish (Rhopilema esculentum) matrices decellularized with seven different detergents. All of them showed effectiveness in removing the cellular components.
[Journal Of Materials Chemistry B] |
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| In order to counter the flushing effect of gushing blood, a gas-jet propelled powder hemostat ((COL/PS)4@CaCO3-T-TXA+) was developed. (COL/PS)4@CaCO3-T-TXA+ dove into the deep bleeding sites of complex wounds for targeted hemostasis.
[Journal Of Materials Chemistry B] |
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| Researchers developed a new instrument named ‘OptoRheo’ that combined light sheet fluorescence microscopy with particle tracking microrheology.
[Communications Biology] |
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| The authors described a unique laminin 523-containing reticular fibre network around and between follicles that associates with PDGFrecβhighCCL19lowgp38low fibroblastic reticular cells.
[iScience] |
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| Investigators performed analyses “in situ” using tissue samples from smokers, former smokers and non-smokers to better understand how the increase in inflammatory mediators induced by smoking exposure could interfere in bone cells activity leading bone structural changes.
[Scientific Reports] |
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| Scientists describe the preparation and design requirements of nanocomposite hydrogels and discusses their applications and challenges in regenerative medicine, hoping to clarify the relationship between the two.
[Macromolecular Rapid Communications] |
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| The nine-year wait for new clinical data on Promore Pharma’s ensereptide has ended in disaster, with the failure of the polypeptide to reduce scarring in a midphase trial wounding the biotech’s share price.
[Fierce Biotech] |
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| The University of Manchester is among eight institutions to receive a share of £73 million in Wellcome funding to establish a Discovery Research Platform for Cell-Matrix Biology.
[The University of Manchester] |
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| June 4 – 7, 2023
Heidelberg, Germany |
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| | Institut Pasteur – Paris, France |
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| | Wake Forest University – Winston Salem, North Carolina, United States |
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| | University of Gothenburg – Gothenburg, Sweden |
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| | University of Melbourne – Melbourne, Australia |
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