| PUBLICATIONS (Ranked by impact factor of the journal) | Chemotactic Recruitment of Adult Neural Progenitor Cells into Multifunctional Hydrogels Providing Sustained SDF-1α Release and Compatible Structural Support Without chemotactic cues and structural support, cavitary brain lesions typically fail to recruit endogenous neural progenitor cells. Toward resolving this, the authors engineered multifunctional biomaterials comprising injectable gelatin-hydroxyphenylpropionic acid hydrogels and dextran sulfate/chitosan polyelectrolyte complex nanoparticles that delivered stromal cell-derived factor-1α (SDF-1α). [FASEB J] Abstract Rap1 Can Bypass the FAK-Src-Paxillin Cascade to Induce Cell Spreading and Focal Adhesion Formation Researchers investigated cell spreading induced by activation of the small GTPase, Rap1. After replating and initial adhesion, unstimulated cells exhibited extensive protrusion and retraction as their spread area increased, and displayed an angular shape that was remodeled over time. [PLoS One] Full Article PLLA-Collagen and PLLA-Gelatin Hybrid Scaffolds with Funnel-Like Porous Structure for Skin Tissue Engineering Hybrid scaffolds were prepared by forming funnel-like collagen or gelatin sponge on a woven poly(l-lactic acid) (PLLA) mesh. The hybrid scaffolds combined the advantages of both collagen or gelatin and PLLA mesh. [Sci Technol Adv Mater] Abstract | Press Release Processed Xenogenic Cartilage as Innovative Biomatrix for Cartilage Tissue Engineering: Effects on Chondrocyte Differentiation and Function The authors developed a decellularization and sterilization process that maintains the three-dimensional collagen structure of native septal cartilage while increasing matrix porosity, which is considered to be crucial for cartilage tissue engineering. [J Tissue Eng Regen Med] Abstract Matrix Metalloproteinase-2 and -9 Lead to Fibronectin Degradation in Astroglia Infected with Toxoplasma gondii Astroglia were infected with the TS-4 strain of Toxoplasma gondii tachyzoite in vitro to investigate the changes of matrix metalloproteinase (MMP)-2, MMP-9 and their substrate fibronectin. [Acta Trop] Abstract Collagen-Nanofiber Hydrogel Composites Promote Contact Guidance of Human Lymphatic Microvascular Endothelial Cells and Directed Capillary Tube Formation Growth, migration, elongation, and tube formation of human lymphatic microvascular endothelial cells were investigated on electrospun poly(d,l-lactic-co-glycolic acid) and poly(l-lactic-co-d-lactic acid) nanofiber-coated substrates, and correlated with fiber density and diameter. [J Biomed Mater Res A] Abstract Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stromal Cells via Biomimetic and Bioactive Poly-ε-Caprolactone Scaffolds Scientists developed a scaffold for mesenchymal stromal cell recruitment, proliferation, and chondrogenic differentiation. The concept behind the design was to mimic the cartilage matrix and contain stimulatory agents that make continuous supply of inductive factors redundant. [J Biomed Mater Res Part A] Abstract Proliferation of Genetically Modified Human Cells on Electrospun Nanofiber Scaffolds To overcome the issue of reduced proliferation phenotype problem, investigators utilized nanofiber scaffolds as templates on which modified cells were allowed to recover, grow, and expand after gene editing. [Mol Ther Nucleic Acids] Abstract |
| JOB OPPORTUNITIES | Scientist or Engineer – hPSC Bioengineer (STEMCELL Technologies, Inc.) Product Quality Scientist (STEMCELL Technologies, Inc.) Scientist – Endothelial Cell Research (STEMCELL Technologies, Inc.) Scientist or Engineer – hPSC Bioengineer (STEMCELL Technologies, Inc.) Quality Control Analyst (STEMCELL Technologies, Inc.) Research Technologist – Cell Separation (STEMCELL Technologies, Inc.) Postdoctoral Position – Tissue Engineering (Weizmann Institute of Science) Postdoctoral Position – Matrix Biology (University of Washington) Postdoctoral Position(s) – Nanomedicine/Bioengineering (Ian Wark Research Institute) Postdoctoral Position(s) – Nanotechnology, Scaffold Engineering, and Biomaterials (University of Michigan) Senior Researcher Position – Biomaterials for Regenerative Medicine (University of Aveiro) Postdoctoral Position – Bioengineering of Heart Tissue and Scaffolds (Masonic Medical Research Laboratory, Utica) Recruit Top Talent: Reach more than 55,000 potential candidates by posting your organization’s career opportunities on the Connexon Creative Job Board at no cost. |
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