 | | Vol. 14.08 – 14 March, 2023 |
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| Investigators systematically analyzed the higher-order chromatin in purified populations of primary human erythroblasts.
[Nature Structural & Molecular Biology] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists provided mechanistic evidence that LYN regulated the polarization of stromal fibroblasts to support leukemic progression. LYN was overexpressed in fibroblasts of lymph nodes of chronic lymphocytic leukemia patients.
[Nature Communications] |
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| Researchers reported that histone deacetylase (HDAC) 3 was highly expressed in the acute promyelocytic leukemia subtype of AML, and the protein level of HDAC3 was positively associated with PML-RARα.
[Cell Death & Differentiation] |
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| Scientists found that significant percentages of lymphocytes were not derived from HSCs. Multiple waves of hematopoiesis occured from embryonic day (E) 7.5 to E11.5 endothelial cells, which simultaneously produced HSCs and lymphoid progenitors in adult mice.
[Cell Reports] |
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| Glucagon-like peptide-1 receptor expression in fluorescence-activated cell sorting-sorted wild-type hematopoietic stem/progenitor cells was determined by capillary western blotting.
[Journal of Molecular Cell Biology] |
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| Investigators reported a novel association and the novel potential pathways for copper overload to induce proliferation defects in zebrafish embryonic hematopoietic stem and progenitor cells (HSPCs) via down-regulating expression of foxm1-cytoskeleton axis.
[iScience] |
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| The authors used peripheral blood collected from patients with peripheral artery disease and performed hind limb ischemia in Apoe−/− mice fed a Western diet and C57BL/6J mice with a standard laboratory diet.
[Arteriosclerosis Thrombosis And Vascular Biology] |
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| Scientists selected patients with the following characteristics: CART or allogeneic hematopoietic cell transplantation (alloHCT) performed between 2016 and 2021; ≥18 years old; aggressive B-cell lymphomas diagnosis; ≥2 lines of therapy; and either anti-CD19 CART or alloHCT as therapy at relapse.
[Bone Marrow Transplantation] |
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| Researchers explored the relationship between the neuronal calcium sensor 1 expression level and cytogenetically normal AML.
[The Pharmacogenomics Journal] |
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| The authors provide a synopsis of the cellular and molecular constituents that participate in bone turnover and their known connections to the hematopoietic compartment.
[Bone Research] |
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| Cytek Biosciences, Inc. announced the launch of a new 20-Color AML Panel. This is a new single-tube flow panel that will allow researchers to quickly and efficiently run AML analysis on any Cytek® Aurora or Northern Lights™ system equipped with violet, blue, and red lasers.
[Cytek® Biosciences] |
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| April 16 – 19, 2023
Snowbird, Utah, United States |
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| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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| | Lund University – Lund, Sweden |
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| | Karolinska Institute – Solna, Sweden |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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