 | | Vol. 6.13 – 8 April, 2022 |
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| Scientists studied heterogeneity of hepatic vascular cells during mouse development through functional and single-cell RNA-sequencing.
[Cell Stem Cell] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators showed that ketohexokinase expression was tightly controlled and limited to a small number of organs and was down-regulated in liver and intestinal cancer cells.
[Science Advances] |
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| The authors identified reverse signaling between glucocorticoid-induced tumour necrosis factor receptor (GITR) and its ligand (GITRL) as a cross-interaction pathway between immune cells and hepatic stem/progenitor cells that restricted the expansion of hepatic stem/progenitor cells and reduced the possibility of carcinogenesis.
[Cell Death & Disease] |
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| Researchers studied the proferroptosis effect and mechanism of mesenchymal stem cell-ex in hepatic stellate cells.
[Cell Death & Disease] |
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| The authors investigated the differential regulatory effect of metabotropic glutamate receptor 5 on chemosensitivity in HCC and chemotoxicity to the normal liver.
[Cancer Gene Therapy] |
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| Scientists found that specific deletion of Cbl-b and c-Cbl in CD11c+ cells, predominantly in dendritic cells (DCs), led to liver fibrosis, cirrhosis, and accumulation of systemic conventional Type I DCs due to enhanced cell proliferation and decreased cell apoptosis.
[Cell Death Discovery] |
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| The biological role and mechanism of nociceptin receptor in HCC tumor growth was determined in vitro and in vivo.
[Cell Death Discovery] |
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| Researchers investigated the role of proprotein convertase subtilisin kexin type 9 (PCSK9) and explored the therapeutic effect of metformin for olanzapine-associated non-alcoholic fatty liver disease.
[Scientific Reports] |
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| Investigators suggested that LRP1B played an essential role in the promotion of HCC progression by regulating the PERK-ATF4-CHOP signaling pathway, which is a potential prognostic biomarker and a promising therapeutic target of HCC.
[Bioengineered] |
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| After co-culture systems of M2 macrophages and HCC cells were established, it was shown that co-culture with M2 macrophages could promote both the proliferation and invasion of HepG2 and Huh7 cells.
[Bioengineered] |
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| The authors summarize the biogenesis, characterization and biological functions, recent detection and identification technologies of circRNA, and regulation network mechanism of circRNA in liver diseases
[Cancer Cell International] |
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| Mursla announced that it has secured mentorship support from Roche Diagnostics, Ltd. for a new liquid biopsy prospective pilot study for liver cancer surveillance through MedCity’s Collaborate to Innovate: London Diagnostics program.
[Mursla] |
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| June 9 – 13, 2022
Washington, DC, United States |
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| | Icahn School of Medicine at Mount Sinai – New York, New York, United States |
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| NIH National Institute on Alcohol Abuse and Alcoholism – Bethesda, Maryland, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | Genentech, Inc. – South San Francisco, California, United States |
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| | Gilead Sciences – Foster City, California, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
