 | | Vol. 6.29 – 12 August, 2022 |
| |
|
|
| Berberine repressed the abnormal transcription of leptin stimulated by lysophosphatidic acid (LPA)-induced phosphorylation of p38 in hepatoma cells.
[Molecular Therapy Oncolytics] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Scientists investigated the role of mitochondrial dynamics in hepatic stellate cell (HSC) activation and the underlying mechanisms. They verified that mitochondrial fission was enhanced in human and mouse fibrotic livers and active HSCs.
[Cell Death & Disease] |
|
|
|
| Researchers showed that heat shock factor 1 messenger RNA was induced in human cirrhotic and murine fibrotic livers.
[Hepatology Communications] |
|
|
|
| Investigators established in vivo and in vitro models of hepatic ischemia reperfusion (IR) and mild hypothermia pretreatment to investigate the protectice mechanism of mild hypothermia in liver IR injury.
[Apoptosis] |
|
|
|
| The authors provided a comprehensive single-cell analysis of non-alcoholic steatohepatitis (NASH) pathology in humans, describing 19,627 single-cell transcriptomes from biopsy-proven NASH patients.
[Scientific Reports] |
|
|
|
| Investigators showed that chronic high androgen levels caused hepatic steatosis while hepatocyte-specific androgen receptor-knockout rescued this phenotype.
[Endocrinology] |
|
|
|
| Coculture of hepatocytes with hepatic stellate cells enhanced intracellular lipid accumulation, together with the upregulation of PPARγ and CD36 protein expressions.
[Journal of Gastroenterology and Hepatology] |
|
|
|
| Researchers used liver biopsies from healthy cows and cows diagnosed with clinical ketosis to assess alterations in cholesterol synthesis, transport, and excretion.
[Journal of Dairy Science] |
|
|
|
| Scientists established a cadmium (Cd) poisoning model in vitro by co-culturing Cd-exposed and unexposed hepatocytes and found that 18β-glycyrrhetinic acid, a GJIC inhibitor, could effectively reduce the apoptosis rate of healthy cells co-cultured with apoptotic cells treated with Cd.
[Environmental Toxicology] |
|
|
|
| Bilirubin glucuronidation activity was examined in canine and human primary hepatocyte spheroids formed using a 3D culture system.
[In Vitro Cellular & Developmental Biology – Animal] |
|
|
|
|
|
| Investigators review our current understanding of innate lymphoid cells in cancer with a particular focus on liver and liver-related diseases.
[Cellular & Molecular Immunology] |
|
|
|
| The authors review recent advances in the interactions between hepatocytes and surrounding cells and among nonparenchymal cells in the context of liver epithelial cell self-replication and discussed the crosstalk of several cell types in the context of liver epithelial transdifferentiation.
[Cell Communication and Signaling] |
|
|
|
| Scientists provide a comprehensive summary of the latest progress in the investigation of chemotherapy resistance concerning noncoding RNAs to promote tailored individual treatment for HCC patients.
[Cancer Cell International] |
|
|
|
|
| Captor Therapeutics S.A. announced that it has selected CPT-6281 as drug candidate for the CT-01 project, which will initially focus on the clinical development of the asset as a targeted protein degradation treatment against HCC.
[Captor Therapeutics S.A.] |
|
|
|
|
| December 8 – 10, 2022
Los Angeles, California, United States |
|
|
|
|
|
| | NIH National Cancer Institute – Bethesda, Maryland, United States |
|
|
|
| | University of Kansas Medical Center – Kansas City, Kansas, United States |
|
|
|
| | Gilead Sciences, Inc. – Foster City, California, United States |
|
|
|
| | Mayo Clinic – Scottsdale, Arizona, United States |
|
|
|
| | University of North Carolina at Greensboro – Kannapolis, North Carolina, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
