 | | Vol. 7.44 – 24 November, 2023 |
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| Atp8b1 regulated hepatic choline levels through intestinal lysoPC absorption, encouraging the evaluation of choline supplementation therapy for steatohepatitis caused by ATP8B1 dysfunction.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers reported a simple and one-pot synthesis of ultrasmall poly(acrylic) acid-coated Mn3O4 nanoparticles which performed multiple antioxidant enzyme-mimicking activities and could scavenge broad-spectrum reactive oxygen species.
[Nature Communications] |
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| Investigators presented a novel, multicellular liver organoid model using a co-culture system of macrophages and liver organoids differentiated from the same human pluripotent stem cells.
[Hepatology] |
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| Scientists revealed the contributions of NRCAM to liver cancer stem cell function and HCC metastasis, and further explored its mechanism in detail.
[Journal Of Experimental & Clinical Cancer Research] |
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| Researchers undertook translational studies in human and mouse orthotopic liver transplantation to interrogate the significance of hepatocyte-specific Sirtuin 1 (SIRT1) in cold-stored donor livers and liver grafts after reperfusion.
[Cell Death & Disease] |
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| Researchers explored therapeutic umbilical cord (UC)-MSC phenotypes for improving liver fibrosis.
[Journal Of Translational Medicine] |
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| Scientists identified multiple ubiquitin-specific proteases (USPs) that could stabilize ABHD17C by inhibiting the ubiquitin-proteasome-mediated degradation.
[Cell Death Discovery] |
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| Investigators evaluated the prognosis and pharmacological therapy sensitivity of epithelial mesenchymal transition-related genes that obtained from the EMTome database in HCC using bioinformatical method.
[Scientific Reports] |
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| Researchers generated three-dimensional multi-cell-type liver organoids from HepaRG cells, primary human macrophages, and hepatic-stellate-cell-derived LX-2 cells.
[Toxicology In Vitro] |
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| The authors aim to comprehensively evaluate the current state of methods for tracking stem cells, highlighting their strengths and weaknesses, and providing insights into their future potential.
[Stem Cell Reviews And Reports] |
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| Hepion Pharmaceuticals, Inc. announced additional efficacy data for rencofilstat, its lead drug candidate for the treatment of metabolic dysfunction-associated steatohepatitis, fibrotic diseases, HCC, and other chronic diseases.
[Hepion Pharmaceuticals, Inc.] |
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| December 16 – 20, 2023
Waikoloa Beach, Hawaii, United States |
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| | Animal & Plant Health Agency – Addlestone, England, United Kingdom |
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| | Babraham Institute – Cambridge, England, United Kingdom |
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| | University of Oxford – Oxford, England, United Kingdom |
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| | Armenian Bioinformatics Institute – Yerevan, Armenia |
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| | Cedars-Sinai – Los Angeles, California, United States |
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