 | | Vol. 8.01 – 12 January, 2024 |
| |
|
|
| To induce spontaneous or forced liver metastasis in mice, murine cancer cells or colon tumor organoids were injected into the cecum or the spleen, respectively.
[Journal Of Hepatology] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Scientists found that the tumor suppressor p53 drove the Kennedy pathway via PCYT1B to control the growth of lipid droplets (LDs) and their fueling role in tumorigenesis. p53 channeled depleted choline stores to phosphatidylcholine biosynthesis during choline starvation, thus preventing LD coalescence.
[Journal Of Clinical Investigation] |
|
|
|
| Researchers explored the mechanistic basis of metabolic syndrome by recruiting an essential patient cohort and performing extensive gene expression profiling.
[EMBO Journal] |
|
|
|
| Investigators proposed an antifibrotic strategy that combined prosenescence with enhanced immune clearance through targeted delivery of manganese via albumin-mediated transcytosis, specifically aimed at inducing senescence and eliminating activated hepatic stellate cells in liver fibrosis.
[Nano Letters] |
|
|
|
| Scientists developed basic fibroblast growth factor (bFGF)-releasing nanoparticles to prolong the survival of hepatocyte sheets after transplantation.
[Journal Of Controlled Release] |
|
|
|
| Scientists explored the mechanism of Hedyotis diffusa–Scutellaria officinalis pair (HD-SB) in the treatment of HCC. A total of 217 active ingredients of HD–SB and 1196 HCC-related targets were reserved from the TCMSP and the SwissTarget Prediction database.
[Scientific Reports] |
|
|
|
| The depletion of sestrin2 resulted in excessive necroptosis, accompanied by increased fat accumulation, inflammation, and oxidative stress in the experimental steatohepatitis model.
[Molecular Metabolism] |
|
|
|
| Researchers aimed to improve HCC therapy by evaluating combination treatment using anti-cancer and anti-fibrosis drugs via identification of novel anti-fibrosis drugs.
[Scientific Reports] |
|
|
|
| Scientists established and validated a prognostic signature of disulfidptosis-related lncRNAs and analyzed tumor microenvironment and drug susceptibility in liver hepatocellular carcinoma patients.
[Scientific Reports] |
|
|
|
| Researchers evaluated the possible role of OMA1/YME1L in HCC staging and discussed their potential role in cellular apoptosis and proliferation. They used four groups of male albino rats: a normal control and three diethyl nitrosamine-treated groups for 8, 16, and 24 weeks.
[Yale Journal Of Biology And Medicine] |
|
|
|
|
|
| The authors elucidate the multifaceted biological functions of N6-methyladenosine modifications in HCC, and concurrently advancing novel therapeutic strategies for the management of this malignancy.
[Acta Pharmacologica Sinica] |
|
|
|
|
| Dozens of science and technology development payloads returned to Earth from the ISS as SpaceX’s 29th Commercial Resupply Services (CRS) mission, contracted by NASA, successfully concluded. An investigation from the University of California, San Francisco focused on aging and liver regeneration.
[ISS National Lab] |
|
|
|
|
| February 11 – 16, 2023
Barga, Italy |
|
|
|
|
|
| | National University of Singapore – Singapore, Singapore |
|
|
|
| | University of California San Francisco – San Francisco, California, United States |
|
|
|
| | Human Technopole – Milan, Italy |
|
|
|
| | Virginia Tech – Blacksburg, Virginia, United States |
|
|
|
| | University of California San Francisco – San Francisco, California, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
