|
|
Vol. 12.02 – 16 January, 2024
|
|
|
|
|
|
|
|
The authors showed that cell surface marker recognition by antibody fragments displayed on membrane-derived particles encapsulating CRISPR–Cas9 protein and guide RNA could deliver genome editing tools to specific cells.
[Nature Biotechnology]
|
|
|
|
|
|
PUBLICATIONSRanked by the impact factor of the journal
|
|
|
|
|
|
Investigators described a reliable platform capable of up to 2,000-fold expansion of human type 2 innate lymphoid cells (ILC2s) within four weeks, whose molecular and cellular ILC2 profiles were validated by single-cell RNA sequencing.
[Cell]
|
|
|
|
|
|
NK cell activation on NKp44/HLA-DP interactions was assessed in vitro using plate-bound HLA-DP molecules and HLA-DPB wildtype versus knock-out human cholangiocyte organoids.
[Gut]
|
|
|
|
|
|
Scientists developed a technique to restrict genetic recombination to regulatory T cells (Tregs) only in skin. Selective depletion of skin Tregs resulted in T cell–mediated inflammation of hair follicles
[Science Immunology]
|
|
|
|
|
|
Magnetic nanoparticles conjugated with anti-CD3 mAb (Ab-MNPs) were characterized using transmission and scanning electron microscopy, and their distribution was assessed using a nanoparticle tracking analyzer.
[Advanced Science]
|
|
|
|
|
|
Piezoelectric catalysis was utilized to reduce intracellular NAD+ to NADH for local tumor cell senescence for the first time.
[Small]
|
|
|
|
|
|
Scientists tested the hypothesis that type-2 inflammation indicated by elevated blood eosinophils and fraction of exhaled nitric oxide would be associated with accelerated lung function decline in the general population.
[Thorax]
|
|
|
|
|
|
The testicular germ cell tumor transcriptome data in The Cancer Genome Atlas Program database was used to perform consensus clustering analysis to construct a prognostic model for testicular germ cell tumors.
[Heliyon]
|
|
|
|
|
|
Researchers found that the key factors of glutamine metabolism, glutaminase 1 (GLS) and mitochondrial aspartate transaminase (GOT2), showed opposite expression patterns in breast cancer samples.
[Heliyon]
|
|
|
|
|
|
|
|
Scientists highlight advances in each antibody–drug conjugate component — the monoclonal antibody, payload, linker and conjugation chemistry — and provide detailed discussions on selected examples of emerging novel antibody–drug conjugates of each format.
[Nature Reviews Clinical Oncology]
|
|
|
|
|
|
The authors focus on the members of this receptor family expressed on immune cells and how they govern immune and neuro-immune pathways underlying various physiological and pathological states.
[Immunity]
|
|
|
|
|
|
|
|
Until now, Tecentriq has been given directly into patients’ veins by IV infusion which takes approximately 30-60 minutes. The new subcutaneous injection will cut treatment time to approximately seven minutes, with most injections taking between four and eight minutes.
[Roche]
|
|
|
|
|
|
|
|
February 11 – 16, 2023
Barga, Italy
|
|
|
|
|
|
|
|
|
|
|
Karolinska Institutet – Solna, Sweden
|
|
|
|
|
|
|
Sanofi – Cambridge, Massachusetts, United States
|
|
|
|
|
|
|
Roche – Penzberg, Germany
|
|
|
|
|
|
|
Guangzhou Institutes of Biomedicine and Health – Guangzhou, China
|
|
|
|
|
|
|
Northwestern University – Chicago, Illinois, United States
|
|
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News