 | | Vol. 12.14 – 16 April, 2024 |
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| To assess uterine immune system variation, investigators performed a system-level analysis of endometrial and peripheral blood immune cells in monozygotic twins.
[Science Immunology] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers investigated the effect of NMU/NMUR1 axis on early activation of group 2 innate lymphoid cells in asthma. Mild asthmatics were enrolled in a diluent-controlled, allergen-inhalation challenge study.
[American Journal Of Respiratory And Critical Care Medicine] |
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| Single-cell RNA and T cell receptor sequencing were performed on renal biopsy tissues from 40 patients with lupus nephritis (LN) and 6 healthy donors as controls. Matched peripheral blood samples from seven LN patients were also sequenced.
[Annals Of The Rheumatic Diseases] |
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| Using single-cell RNA sequencing data from the Gene Expression Omnibus database, the study identified distinct gene expression patterns in tumor-infiltrating B cells.
[International Journal Of Oral Science] |
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| Scientists comprehensively profiled 100 human uveal melanoma metastases using clinicogenomics, transcriptomics, and tumor infiltrating lymphocyte potency assessment.
[Nature Communications] |
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| Investigators presented the results of a Phase I clinical trial in which a dendritic cell vaccine targeting patient-individual neoantigens is evaluated in patients with resected non-small cell lung cancer.
[Cell Reports Medicine] |
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| The authors investigated CD4+ and CD8+ T lymphocytes from the synovial tissue and peripheral blood of patients with treatment-resistant immune-mediated arthritis using paired single-cell RNA and TCR-sequencing.
[Molecular Medicine] |
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| Scientists assessed the immune cell composition of peri-implantitis and periodontitis lesions and the corresponding inflammatory profile in soft tissues and crevicular fluid. Peri-implantitis, periodontitis, and control patients were recruited, and soft tissue biopsies were collected during surgery.
[Clinical & Experimental Metastasis] |
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| Weighted gene coexpression network analysis helped identify memory CD4+ T cell–associated gene modules. Combined with module genes, a five-gene lung adenocarcinoma prognostic risk model was constructed by regression analysis.
[CPT-Pharmacometrics & Systems Pharmacology] |
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| The authors cover the state-of-the-art in the intricate landscape of immune organs-on-chip models, shedding light on the pivotal role of biofabrication technologies in bridging the gap between conceptual design and physiological relevance.
[Advanced Healthcare Materials] |
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| Biochemist and structural biologist Robert Tampé, a specialist in the structural analysis of membrane protein complexes of the adaptive immune system, has been awarded a five-year, €2.5 million European Research Council Advanced Grant.
[Goethe University Frankfurt (EurekAlert!)] |
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| Sooner than you may think, says Dr. Catherie Wu, Harvard Medical School professor of medicine and, was honored in February with the $1 million Sjöberg Prize, given for cancer research.
[Harvard Medical Soon] |
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| May 20, 2024
New York, New York, United States & Online |
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| | Boston University – Boston, Massachusetts, United States |
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| | Indiana University School of Medicine – Indianapolis, Indiana, United States |
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| | Boston University – Boston, Massachusetts, United States |
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| | University of Wisconsin-Madison – Madison, Wisconsin, United States |
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| | Yale University – New Haven, Connecticut, United States |
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