 | | Vol. 16.01 – 12 January, 2024 |
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| The authors found that mice harboring the microbiota of wild-caught mice developed overt colitis following treatment with anti-cytotoxic T-lymphocyte protein 4 (CTLA-4) antibodies.
[Science] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Combining Kaede photoconvertible mice and single-cell genomics, investigators generated a detailed map of migratory trajectories from the colon, at baseline, and in several models of intestinal and extraintestinal inflammation.
[Science Immunology] |
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| By performing single-cell RNA sequencing in colorectal cancer tissues, researchers found tumor-associated macrophages and granulocytic myeloid-derived suppressor cells increased most compared to their counterparts in normal tissue.
[Nature Cancer] |
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| A twindrive precise delivery system of hybrid membrane combined with CD47 blocking was developed for targeted delivery and targeted regulation to induce postoperative immunotherapy.
[ACS Nano] |
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| Scientists identified a conserved signaling cascade that led to Hippo pathway activation by innate immune/inflammatory signals.
[Nature Communications] |
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| Researchers revealed that the impact of Eomes on effector CD4+ T cell longevity was associated with sustained expression of multiple genes involved in mitochondrial organization and functions.
[Journal Of Experimental Medicine] |
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| The authors discovered that blocking the PI3Kδ pathway pharmaceutically to varying degrees could generate T cells with increasingly heightened stemness properties, based on the progressive enrichment of the transcription factors Tcf1 and Lef1.
[Cancer Research] |
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| Investigators elucidated the underlying mechanism of Ars. alb 30C-mediated immune priming in murine macrophage cell line.
[Scientific Reports] |
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| The authors discuss the interplay between myeloid-derived suppressor cells (MDSCs) and various other cell types found in tumors as well as the mechanisms by which MDSCs promote tumor progression.
[Nature Reviews Clinical Oncology] |
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| The National Institutes of Health has awarded the Oklahoma Medical Research Foundation $5.8 million to work toward easier diagnosis and better treatment options for Sjögren’s disease, an autoimmune condition.
[Oklahoma Medical Research Foundation] |
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| February 14 – 16, 2024
Lorne, Australia |
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| | University of Illinois at Chicago College of Medicine – Chicago, Illinois, United States |
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| | Northwestern University – Chicago, Illinois, United States |
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| | Albert-Ludwigs-University Freiburg – Freiburg im Breisgau, Germany |
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| | Francis Crick Institute – London, England, United Kingdom |
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| | Institut Pasteur – Paris, France |
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