 | | Vol. 10.24 – 22 June, 2022 |
| |
|
|
| Researchers demonstrated that peptidoglycan underpinned the spatiotemporal organization of outer membrane proteins.
[Nature] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
| |
|
|
| Based on 78 vaccine efficacy or effectiveness (VE) data from 49 studies and 1,984,241 SARS-CoV-2 sequences collected from 31 regions, scientists analyzed the relationship between genetic distance of circulating viruses against the vaccine strain and VE against symptomatic infection.
[Nature Medicine] |
|
|
|
| Investigators searched for drivers of variant of concern-like emergence by consolidating sequencing results from a set of 27 chronic SARS-CoV-2 infections.
[Nature Medicine] |
|
|
|
| Scientists conducted an age de-escalation study to assess the safety, reactogenicity, and immunogenicity of an inactivated COVID-19 vaccine, BBV152, in children aged 2-18 years.
[Lancet Infectious Diseases] |
|
|
|
| Researchers identified and characterized antigen-specific cells and antibody responses to the RNA vaccine BNT162b2 using multiple single-cell technologies for in depth analysis of longitudinal samples from a cohort of healthy participants.
[Nature Communications] |
|
|
|
| The authors described the mechanisms by which the E protein of SARS-CoV-2 hijacked the human transcriptional regulator BRD4.
[Structure] |
| | MORE IMMUNOLOGY OF INFECTIOUS DISEASE |
|
|
|
| Computational transcriptomics and Xenopus laevis embryos were used to discover infection response pathways, identify potential tolerance inducer drugs, and validate their ability to induce broad tolerance.
[Advanced Science] |
|
|
|
| Researchers identified mandibular lymph nodes as sentinel lymphoid organs that intercepted ingested Listeria monocytogenes.
[Science Immunology] |
|
|
|
| Using host microRNA-mediated vector tropism restriction, scientists showed that the priming of major histocompatibility complex (MHC)-II and MHC-E epitope–targeted responses depended on vector infection of different nonoverlapping cell types in rhesus macaques.
[Science Immunology] |
|
|
|
| Investigators reported that following viral infection, Tet2-deficient CD4+ T cells preferentially differentiated into highly functional germinal center T follicular helper cells that provided enhanced help for B cells.
[Science Advances] |
|
|
|
| Researchers reported the 3.39 Å cryo-electron microscopy structure of trimeric, prefusion RABV-G complexed with RVA122, a potently neutralizing human antibody, providing a basis from which to develop improved rabies vaccines.
[Science Advances] |
|
|
|
| Scientists showed that the combination of active and passive immunization with vesatolimod may have led to higher rates of post-antiretroviral therapy virologic control compared to either approach alone.
[Nature Communications] |
|
|
|
| The authors found that experimentally infected mice resolved Bartonella infection by mounting antibody responses that neutralized the bacteria, preventing their attachment to erythrocytes and suppressing bacteremia independent of complement or Fc receptors.
[Proceedings of the National Academy of Sciences of the United States of America] |
|
|
|
|
| Scientists describe advances in antibody discovery and engineering that have led to the development of monoclonal antibodies for use against infections caused by viruses including SARS-CoV-2, respiratory syncytial virus, Ebola virus, human cytomegalovirus, and influenza.
[Nature Reviews Drug Discovery] |
|
|
|
| The accurate characterization of nanovaccines can be conceptualized as a combination of physicochemical, immunological, and toxicological assays.
[Nature Nanotechnology] |
|
|
|
| The immune system has a dual role as protector and cause of disease: in addition to being protective, increasing evidence shows that innate immune responses can become excessive and cause acute symptoms and tissue pathology during infection.
[Nature Reviews Urology] |
|
|
|
|
| Humanigen, Inc. announced it has entered into an agreement with PCI Pharma Services to provide importation, release, and commercialization services in the United Kingdom for lenzilumab.
[Humanigen, Inc.] |
|
|
|
| Olink Holding AB announced that the Human Genomics Facility of the Erasmus Medical Center in Rotterdam has adopted the Olink technology, becoming the first Olink® Explore certified laboratory in the Netherlands.
[Olink Holding AB] |
|
|
|
| Pfizer, Inc. and BioNTech SE announced the US FDA has granted emergency use authorization of the Pfizer-BioNTech COVID-19 Vaccine as a three 3-µg dose series for children six months through four years of age.
[Pfizer, Inc.] |
|
|
|
| Adaptive Biotechnologies Corporation announced the launch of T-Detect™ Lyme. The T-Detect test detects an immune response by leveraging the body’s unique T cell response to disease-associated antigens.
[Adaptive Biotechnologies Corporation] |
|
|
|
|
| September 19 – 20, 2022
Vejle, Denmark |
|
|
|
|
|
| | University of Copenhagen – Copenhagen, Denmark |
|
|
|
| | University of Gothenburg – Gothenburg, Sweden |
|
|
|
| | Boston Children’s Hospital – Boston, Massachusetts, United States |
|
|
|
| | Temple University – Philadelphia, Pennsylvania, United States |
|
|
|
| | National Institute of Allergy and Infectious Diseases – Bethesda, Maryland, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
