 | | Vol. 11.12 – 29 March, 2023 |
| |
|
|
| Using the cecal ligation and puncture model of sepsis, scientists observed septic thrombosis and neutrophil extracellular trap formation within the mouse vasculature by intravital microscopy.
[Immunity] |
|  |
|
|
| PUBLICATIONSRanked by the impact factor of the journal |
| |
|
|
| Investigators tested the neutralizing activity of 482 human monoclonal antibodies isolated from people who received two or three mRNA vaccine doses, or from people vaccinated after infection.
[Nature Communications] |
|
|
|
| Humoral and cellular immune responses against seasonal human coronavirus OC43 and SARS-CoV-2 were assessed in SARS-CoV-2-unexposed children and adults.
[Proceedings Of The National Academy Of Sciences Of The United States Of America] |
|
|
|
| Researchers used airway organoids to screen a chemical library of autophagic modulators to identify compounds that could potentially be used to fight against infections by a broad range of coronaviruses.
[Molecular Pharmaceutics] |
| | MORE IMMUNOLOGY OF INFECTIOUS DISEASE |
|
|
|
| The authors studied the contributions of canonical and non-canonical autophagy in the genetically tractable human induced pluripotent stem cell-derived macrophages, using a set of Mycobacterium tuberculosis mutants generated in the same genetic background of the common lab strain H37Rv.
[Nature Microbiology] |
|
|
|
| Combined deficiency of DNASE1 and DNASE1L3 rendered mice susceptible to bloodstream infection with Staphylococcus aureus.
[Journal Of Experimental Medicine] |
|
|
|
| Ubiquitin-like protein BMSC-UbP (UBL7)-deficient mice exhibited increased susceptibility to viral infection due to attenuated antiviral innate immunity. UBL7 enhanced innate immune response to viral infection by promoting the K27-linked polyubiquitination of mitochondrial antiviral signaling protein (MAVS).
[Cell Reports] |
|
|
|
| The authors showed a significant reduction in interferon-β induction and a corresponding increase in viral replication in norovirus-infected cells after deletion of STING, cGAS, or IFI16.
[Cell Reports] |
|
|
|
| Temsavir prevented shed gp120 from interacting with uninfected bystander CD4+ cells, protecting them from antibody-dependent cellular cytotoxicity responses and preventing a cytokine burst.
[Cell Chemical Biology] |
|  |
|
|
|
| The authors provide an update of the latest scientific and clinical evidence on vitamin D and immune response in autoimmune rheumatic diseases and COVID-19, which justify the need for monitoring of serum 25(OH)D3 concentrations and for appropriate supplementation following clinical trial-based approaches.
[Nature Reviews Rheumatology] |
|
|
|
|
| The ongoing Marburg fever outbreak in Equatorial Guinea is significantly larger than has previously been acknowledged, according to new information released by the World Health Organization (WHO).
[STAT News] |
|
|
|
| A study found that of the 6-8m urinary tract infections (UTIs) caused by E coli bacteria in the US every year, between 480,000 and 640,000 could be linked to strains known as FZECs, or food-borne zoonotic E coli.
[The Guardian] |
|
|
|
| Through a pair of newly finalized guidance documents, the FDA said it aims to help companies navigate the legal requirements that may shift after the US government formally rolls back its public health emergency authorities.
[Fierce Biotech] |
|
|
|
|
| April 23 – 28, 2023
Cancun, Mexico |
|
|
|
|
|
| | Pfizer, Inc.- Cambridge, Massachusetts, United States |
|
|
|
| | Hudson Institute of Medical Research – Melbourne, Australia |
|
|
|
| | Dana-Farber Cancer Institute and Harvard Medical School – Boston, Massachusetts, United States |
|
|
|
| | Ume̴ University РUme̴, Sweden |
|
|
|
| | University of Cambridge – Cambridge, England, United Kingdom |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
