Immunology of Infectious Disease News Volume 11.43 | Nov 01 2023

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    2023-10-31 | IIDN 11.43


    Immunology of Infectious Disease News by STEMCELL Technologies
    Vol. 11.43 – 1 November, 2023
    TOP STORY

    A Systematic Review and Meta-Analysis of the Global Prevalence and Determinants of COVID-19 Vaccine Acceptance and Uptake in People Living with HIV

    Scientists reported the pooled prevalence of COVID-19 vaccine acceptance/uptake and determinants among this vulnerable population of people living with HIV based on a systematic review and meta-analysis of studies published by 25 August 2023.
    [Nature Human Behaviour]

    Full Article
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    Antiviral Responses in a Jamaican Fruit Bat Intestinal Organoid Model of SARS-CoV-2 Infection

    Investigators established a Jamaican fruit bat intestinal organoid model of SARS-CoV-2 infection.
    [Nature Communications]

    Full Article

    Human In Vitro Modeling of Adjuvant Formulations Demonstrates Enhancement of Immune Responses to SARS-CoV-2 Antigen

    Scientists applied four complementary human in vitro platforms to assess individual and combined adjuvants in unformulated, oil-in-water, and liposomal delivery platforms.
    [NPJ Vaccines]

    Full Article

    Antibody Response and Soluble Mediator Profile in the First Six Months following Acute SARS-CoV-2 Infection

    Researchers presented the chronology of antibodies during six months after infection in hospitalized patients and the kinetics of serum soluble mediators of the cellular response triggered by SARS-CoV-2.
    [Scientific Reports]

    Full Article

    Co-Infection Dynamics of COVID-19 and HIV/AIDS

    Scientists investigated the impact of intervention strategies and identify the role of different parameters in risking people living with HIV to death when they get infected with COVID-19.
    [Scientific Reports]

    Full Article

    Human McTs1-Dependent Translation of JAK2 Is Essential for IFN-γ Immunity to Mycobacteria

    Investigators suggested that X-linked recessive human MCTS1 deficiency underlies isolated mycobacterial disease by impairing JAK2 translation in innate-like adaptive T lymphocytes, thereby impairing the IL-23-dependent induction of interferon-gamma.
    [Cell]

    Full ArticleGraphical Abstract

    Human ApoE2 Protects Mice Against Plasmodium berghei ANKA Experimental Cerebral Malaria

    Human apolipoprotein E (hApoE) mice infected with Plasmodium berghei ANKA showed increased splenomegaly and IFN-γ levels in serum but reduced cerebral cell apoptosis that correlated with the survival advantage against experimental cerebral malaria.
    [mBio]

    Full Article

    CD70-Induced Differentiation of Proinflammatory Th1/17/22/GM Lymphocytes Associated with Disease Progression and Immune Reconstitution During HIV Infection

    Researchers highlighted the role of CD70 in Th1/17/22/GM differentiation during HIV infection and provided evidence for CD70 as a potential biomarker for predicting immune recovery.
    [Virologica Sinica]

    Full Article

    Molecular Mechanism of the Interaction Between Megalocytivirus-Induced Virus-Mock Basement Membrane (VMBM) and Lymphatic Endothelial Cells

    The interactions between virus-encoded VMBM components and lymphatic endothelial cell (LEC)-specific markers lymphatic vessel endothelial receptor-1 and VEGFR-3, which contributed to the selective adhesion of LECs on VMBM, were analyzed.
    [Journal Of Virology]

    Abstract
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    REVIEWS

    Recent Advances in Understanding T Cell Activation and Exhaustion During HBV Infection

    Scientists summarize recent developments in characterizing T cell immunity in HBV infection by reviewing basic and clinical research published in the last five years.
    [Virologica Sinica]

    Full Article

    Ebola Virus Disease in Children: Epidemiology, Pathogenesis, Management, and Prevention

    The authors summarize recent advancements in our understanding of Ebola disease epidemiology, clinical presentation, and therapeutic and preventative strategies.
    [Pediatric Research]

    Abstract
    INDUSTRY AND POLICY NEWS

    Dengue Rates Drop After Release of Modified Mosquitoes in Colombia

    Three cities in Colombia saw a dramatic fall in the incidence of dengue in the years following the introduction of mosquitoes carrying Wolbachia, a bacterium that prevents the insect from transmitting viruses.
    [Nature]

    News Article

    Can Gene Editing Drive Out HIV and Hepatitis Viruses from Inside Cells?

    Armed with gene technologies and CAR-Ts, scientists are attempting to eliminate viruses that escape immune detection and lurk in tissues for years.
    [Nature Biotechnology]

    News Article
    FEATURED EVENT

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    November 26 – 29, 2023
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    JOB OPPORTUNITIES

    Research Assistant – HIV Research

    Rutgers University – New Brunswick, New Jersey, United States

    Faculty Positions – Immunology & Microbiology

    Westlake University – Hangzhou, Zhejiang, China

    Lab Coordinator – Infectious Disease

    University of Minnesota Twin Cities – Minneapolis, Minnesota, United States

    Postdoctoral Position – Post-COVID and COPD Bioinformatics

    Karolinska Institutet – Solna, Sweden

    Research Associate – Department of Infectious Diseases

    King’s College London – Harrow, England, United Kingdom

    > See All Jobs

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