 | | Vol. 11.45 – 15 November, 2023 |
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| Investigators assessed HIV-1-neutralizing immunoglobulin G from 2,354 persons with HIV-1 on or off antiretroviral therapy.
[Nature Medicine] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers conducted a comprehensive population genetic study of over thirteen million SARS-CoV-2 genome sequences, collected over a timeframe of ~3 years, to investigate these forces.
[npj Viruses] |
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| Scientists compared the functional status, level of physical activity, fatigue, and quality of life (QoL) of patients with Long COVID to other COVID-19 patients who did not develop persistent illness, and to determined whether there is a relationship between these variables and QoL.
[Scientific Reports] |
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| Investigators determined the seroconversion rate of neutralizing antibodies against wild-type SARS-CoV-2 and variants of concern at day 28 after the third dose of vaccine and day 28 after the fourth dose of vaccine.
[Scientific Reports] |
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| Researchers implicated heat shock protein 27 as a marker of advanced pathogenesis of disease contributing to the dysregulated systemic inflammation and worse clinical outcomes in COVID-19 acute respiratory distress syndrome and therefore may represent a potential therapeutic target.
[Cell Stress & Chaperones] |
| | MORE IMMUNOLOGY OF INFECTIOUS DISEASE |
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| Scientists employed a chemo-proteomics approach with a bifunctional cholesterol probe and showed that cholesterol was closely associated with the Zika virus structural protein prM.
[Nature Communications] |
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| The authors showed that senescent cells accumulated in aged human brain organoids and that senolytics reduced age-related inflammation and rejuvenated transcriptomic aging clocks.
[Nature Aging] |
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| Scientists investigated the potential role of gasdermin D in promoting the development of severe influenza A virus (IAV) disease. IAV infection resulted in cleavage of GSDMD in vivo and in vitro in lung epithelial cells.
[Cell Death & Disease] |
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| Researchers performed a quantitative proteomic analysis to fully characterize the Nef-induced changes in protein composition of T cell-derived extracellular vesicles and identified novel host targets of HIV.
[Molecular & Cellular Proteomics] |
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| Scientists delve into the potential influence of nirmatrelvir on enduring immunity. In parallel, the potential of drug repurposing is explored, with bisphosphonates being examined for their possible effects against COVID-19 due to their immunomodulatory properties.
[Cellular & Molecular Immunology] |
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| The authors discuss the biological effects of the SARS-CoV-2 virus on post-acute disease in the context of tissue and organ adaptations and damage.
[European Journal Of Human Genetics] |
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| Colleen Jonsson, PhD, director of the Regional Biocontainment Laboratory (RBL) at the University of Tennessee Health Science Center, has been awarded $11.9 million from the National Institute of Allergy and Infectious Diseases to expand and improve the RBL infrastructure.
[The University of Tennessee Health Science Center] |
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| December 6 – 8, 2023
Geneva, Switzerland |
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| | University of Washington – Medical Lake, Washington, United States |
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| | China Pharmaceutical University – Nanjing, Jiangsu, China |
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| | National University of Singapore – Kent Ridge, Singapore |
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| | Rutgers University – New Brunswick, New Jersey, United States |
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| | University of Minnesota Twin Cities – Minneapolis, Minnesota, United States |
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