 | | Vol. 11.46 – 22 November, 2023 |
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| Investigators used cryo-electron tomography to monitor viral envelope glycoprotein-CD4 interactions at the membrane–membrane interfaces formed between HIV-1 and CD4-presenting virus-like particles.
[Nature] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers found that the SARS-CoV-2 variants selected for as the virus evolved from the pre-Alpha to the Delta variant had earlier and higher peak in viral load dynamics but a shorter duration of infection.
[Nature Communications] |
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| A novel bispecific CB6/dendritic cell (DC)-specific intercellular adhesion molecule 3-grabbing nonintegrin nanovesicles were constructed to target both the SARS-CoV-2 spike protein and the DC receptors for virus neutralization and immune activation.
[ACS Biomaterials Science & Engineering] |
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| Scientists assessed the association between COVID-19 vaccines, SARS-CoV-2 infection and the risk of thrombocytopenia and venous thromboembolism.
[Scientific Reports] |
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| Investigators speculated that the adoption of an appropriate technique to inactivate viral particles in saliva specimens allowed the safety maintenance of salivary collections, also during the SARS-CoV-2 outbreak.
[Endocrine] |
| | MORE IMMUNOLOGY OF INFECTIOUS DISEASE |
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| Researchers illuminated intermediate conformations of HIV-1envelope and illustrated its structural plasticity.
[Nature] |
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| The authors prospectively enrolled 72 adult cytomegalovirus (CMV)-seropositive CD19-, CD20-, or BCMA-targeted chimeric antigen receptor-modified T cell immunotherapy (CARTx)-recipients and tested plasma for CMV pre- and weekly up to twelve weeks post-CARTx.
[Clinical Infectious Diseases] |
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| Researchers designed and evaluated single-component self-assembling protein nanoparticles (SApNPs) presenting the conserved extracellular domain of matrix protein 2 as vaccine candidates against influenza A viruses.
[ACS Nano] |
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| Scientists reported the interaction between viral Gag protein and host cell lipids using different quantitative and super-resolution microscopy techniques in combination with specific probes that bind endogenous sphingomyelin and cholesterol.
[Nature Communications] |
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| The authors discuss underlying immunology, changing epidemiology, and updates on the management of cryptococcal meningitis with emphasis on HIV-associated disease.
[Nature Reviews Disease Primers] |
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| Siouxsie Wiles, a microbiologist at the University of Auckland, is suing her employer for failing to adequately address the harassment she received as a result of her public comments during the COVID-19 pandemic.
[Nature] |
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| December 16 – 20, 2023
Waikoloa Beach, Hawaii, United States |
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| | East Tennessee State University – Johnson City, Tennessee, United States |
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| | NIH National Cancer Institute – Bethesda, Maryland, United States |
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| | China Pharmaceutical University – Nanjing, Jiangsu, China |
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| | National University of Singapore – Kent Ridge, Singapore |
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| | Rutgers University – New Brunswick, New Jersey, United States |
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