 | | Vol. 12.11 – 20 March, 2024 |
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| Researchers showed, through studies in mouse models lacking antibodies but maintaining functional B cells and lymphoid organs, that immunity conferred by prior infection or mRNA vaccination could protect against SARS-CoV-2 challenge independently of antibodies.
[Nature Immunology] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| From a cohort of health care personnel, first responders, and other frontline workers in six US states, investigators examined heterogeneity of the effect of hybrid immunity on SARS-CoV-2 antibody levels.
[Clinical Infectious Diseases] |
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| Scientists identified a compound that binds to NSP10 and inhibits its interaction with NSP16, while also disrupting the methyltransferase activity of the complex, and SARS-CoV-2 replication.
[Molecular Systems Biology] |
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| The authors explored whether SARS-CoV-2 infection affected the pregnancy outcomes of assisted reproductive techniques.
[BMC Medicine] |
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| Investigators demonstrated that β-escin and Aesculus hippocastanum L. had antiviral and virucidal activities against SARS-CoV-2 and CCoV, revealing broad-spectrum antiviral activity against coronaviruses.
[Scientific Reports] |
| | MORE IMMUNOLOGY OF INFECTIOUS DISEASE |
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| Scientists established an animal model by infecting cynomolgus macaques with the prevalent MPXV strain, WIBP-MPXV-001, and simulating its natural routes of infection.
[Emerging Microbes & Infections] |
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| Investigators showed that the prefusion conformation of respiratory syncytial virus fusion protein could be stabilized with two engineered dityrosine crosslinks, markedly improving its stability and shelf-life.
[Nature Communications] |
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| Researchers investigated the effect of H. pylori co-infection on CD4+ T cell count and HIV viral load dynamics in HIV-positive individuals in a high co-endemic setting.
[European Journal Of Medical Research] |
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| A novel multivalent MVA-BN-WEV vaccine encoded the envelope surface proteins of the 3 viruses and was thereby potentially able to protect against three encephalitic alphaviruses. This first-in-human study assessed the safety, tolerability, and immunogenicity of MVA-BN-WEV vaccine in healthy adult participants.
[Vaccine] |
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| The authors describe in detail the basic information of ferritin in the first section, including its structural features, the regulation of ferritin. They then focus on the role of ferritin in viral infection-related diseases and the molecular mechanisms by which viral infection regulates ferritin.
[Reviews In Medical Virology] |
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| When it comes to describing scientists whose peer-reviewed studies suggest the COVID-19 virus made a natural jump from animals to humans, molecular biologist Richard Ebright and microbiologist Bryce Nickels have used some very harsh language.
[Science] |
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| Hungarian-American biochemist and researcher Katalin Karikó has been selected by Scripps Institution of Oceanography at UC San Diego as the recipient of the 2023 Nierenberg Prize for Science in the Public Interest.
[UC San Diego Today] |
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| April 22 – 25, 2024
Banff, Alberta, Canada |
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| | Virginia Tech – Blacksburg, Virginia, United States |
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| | The University of Iowa – Iowa City, Iowa, United States |
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| | Indiana University – Indiana, Pennsylvania, United States |
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| | University of Washington – Medical Lake, Washington, United States |
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| | UC Davis – Davis, California, United States |
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