 | | Vol. 9.36 – 22 September, 2021 |
| |
|
|
| Immunoglobulin G from mRNA-immunized nonhuman primates was passively transferred in a highly pathogenic Syrian hamster SARS-CoV-2 challenge model to determine whether these antibodies were sufficient for protection.
[Science] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
| |
|
|
| The authors investigated induction of antigen-specific antibody, B cell and T cell responses longitudinally in patients with multiple sclerosis on anti-CD20 antibody monotherapy compared with healthy controls after BNT162b2 or mRNA-1273 mRNA vaccination.
[Nature Medicine] |
|
|
|
| Investigators found that viral infection promoted the G protein–coupled receptor lysophosphatidic acid (LPA)1 expression, and LPA restrained type I/III interferon production through LPA1.
[Science Advances] |
|
|
|
| Researchers showed that critical COVID-19 was associated with enhanced eosinophil-mediated inflammation when compared to non-critical cases.
[Cell Reports] |
| | MORE IMMUNOLOGY OF INFECTIOUS DISEASE |
|
|
|
| Scientists designed a series of peptides specifically targeting enterovirus A71-encoded protein 3A, a viral suppressor of RNAi. The peptides showed in vitro and in vivo anti-enteroviral efficacy that depends on RNAi.
[Immunity] |
|
|
|
| The authors found the chlamydial parasitophorous vacuole protein CT135 triggered NLRP3 inflammasome activation via TLR2/MyD88 signaling as a pathogenic strategy to evade neutrophil host defense.
[Nature Communications] |
|
|
|
| Investigators developed an HIV-1 promoter-targeting Zinc Finger Protein fused to active domains of DNA methyltransferase 3 A to induce long-term stable epigenetic repression of HIV-1.
[Nature Communications] |
|
|
|
| Scientists demonstrated that a characteristic additional third nuclear factor κB binding site in the long terminal repeat promoter allows subtype C HIV-1 strains to evade restriction by nuclear PYHIN proteins.
[Cell Reports] |
|
|
|
| The authors found that topoisomerase-II was a substrate of the Epstein-Barr virus ubiquitin deconjugase BPLF1.
[PLOS Pathogens] |
|
|
|
| Researchers reported that CXCR3-dependent recruitment of Ly6C+ Th1 effector cells was indispensable for concomitant immunity and acute cell-phagocyte interactions were critical to prevent the establishment of a permissive pathogen niche.
[PLOS Pathogens] |
|
|
|
|
| The authors delineate the structural features of SARS-CoV-2 from the whole viral particle to the individual viral proteins and discuss their functions as well as their potential as targets for therapeutic interventions.
[Nature Reviews Microbiology] |
|
|
|
| Scientists describe chemical signaling systems in E. coli in the context of the broader field of metabolism at the host–bacteria interface and the role of this signaling in disease modulation.
[Nature Chemical Biology] |
|
|
|
|
| The Vaccine and Infectious Disease Organization, known as VIDO, at the University of Saskatchewan is moving to Phase II of clinical testing of a COVID-19 vaccine developed at its lab in Saskatoon.
VIDO (GlobalNews, Inc.) |
|
|
|
| City of Hope is now enrolling patients in a Phase II clinical trial of its COH04S1 vaccine that is the first to study the safety and effectiveness of an investigational vaccine in blood cancer patients who have received a bone marrow transplant or CAR T therapy.
[City of Hope (BusinessWire, Inc.)] |
|
|
|
|
| January 12 – 14, 2022
Shanghai, China |
|
|
|
|
|
| | University of Cambridge – Cambridge, England, United Kingdom |
|
|
|
| | Vanderbilt University Medical Center – Nashville, Tennessee, United States |
|
|
|
| | University of Gothenburg – Gothenburg, Sweden |
|
|
|
| University of Colorado – Aurora, Colorado, United States |
|
|
|
| | Cleveland Clinic – Port Saint Lucie, Florida, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
