| Vol. 10.01 – 12 January, 2024 |
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| Researchers explored the precancerous nature of intestinal metaplasia (IM) by analysing epigenetic alterations. Genome-wide DNA methylation analysis was conducted by EPIC BeadArray using IM crypts isolated by Alcian blue staining. [Gut] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers characterized the molecular features associated with CCR5/CCL5 expression in colorectal cancer and to determine whether CCR5/CCL5 levels could impact treatment outcomes. [Journal for Immunotherapy of Cancer] |
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| Investigators developed a colon dual-targeting nanoparticle, for orally delivering bilirubin through hydrogel encapsulation of hyaluronic acid-modified poly (lactic-co-glycolic acid) nanoparticles. [Theranostics] |
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| The authors found that death receptor 5 gene deletion mice had impaired epithelial absorption and barrier function, resulting in delayed weight gain, which might be related to the general reduction of differentiated epithelial cells. [Cell Death & Disease] |
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| Scientists found that inducible inhibition of β-catenin suppressed elongation of Pol II and RNA polymerase-associated factor 1 complex (PAF1C) around the transcription start site (TSS) of LGR5. [Oncogene] |
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| The authors explored the biological enrichment difference between high- and low-risk patients and found that many carcinogenic pathways were upregulated in the high-risk patients. [Journal Of Cellular And Molecular Medicine] |
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| Researchers characterized the molecular features associated with CCR5/CCL5 expression in colorectal cancer, and to determine whether CCR5/CCL5 levels could impact treatment outcomes. [Journal for Immunotherapy of Cancer] |
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| Diminished FOXO3 activity is associated with human diseases such as obesity, metabolic diseases, inflammatory diseases, and cancer. [American Journal Of Physiology-Gastrointestinal And Liver Physiology] |
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| Gastrointestinal-Graft-versus-host disease causes intestinal immune system disorders, damages intestinal epithelial tissue such as intestinal epithelial cells, goblet, Paneth, and intestinal stem cells, and disrupts the intestinal epithelium’s physical and chemical mucosal barriers. [Transplant Immunology] |
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| It was announced that researchers at UCLA Health Jonsson Comprehensive Cancer Center received two grants totaling $9.1 million from the National Cancer Institute to advance liquid biopsy technologies for the early detection of cancer. [Los Angeles Business Journal] |
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| February 21 – 24, 2024 San Antonio, Texas, United States |
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| University of Pittsburgh – Pittsburgh, Pennsylvania, United States |
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| The Francis Crick Institute – London, England, United Kingdom |
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| University of California San Francisco – San Francisco, California, United States |
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| Human Technopole – Milan, Italy |
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| MD Anderson Cancer Center – Houston, Texas, United States |
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