| Vol. 10.11 – 5 April, 2024 |
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| Researchers identified that MEX3A, frequently upregulated in colorectal cancer tissues, predicted poorer patient survival. [Signal Transduction And Targeted Therapy] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators reported a self-powered electronic bandage made from soft and biodegradable materials that could accelerate wound healing in the intestine. [Nature Electronics] |
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| Researchers reported that colorectal cancer cells that were insensitive to single-agent enhancer of zeste homolog 2 (EZH2) inhibition became sensitive as compensatory lysine-27 trimethylation on histone H3 mediated silencing emerged upon DNA methyltransferase inhibitor treatment. [Science Advances] |
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| Scientists evidenced the role of ubiquitin-specific peptidase 26 (USP26) in promoting colorectal cancer tumorigenesis in a parkin RBR E3 ubiquitin-protein ligase (PRKN) protein-dependent manner. [Oncogene] |
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| The authors investigated the biological effects of lncRNA WAP four-disulfide core domain 21 pseudogene (WFDC21P) in gastric cancer, and reported that WFDC21P downregulation resulted in suppressed proliferation, tumorigenesis, migration, invasion, and promoted apoptosis. [Cancer Cell International] |
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| Analogs of echinomycin, a cyclic peptide natural product with potent toxicity to several human cancer cell lines, were synthesized, and their biological activities against human colon cancer cells were investigated. [Scientific Reports] |
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| Scientists provide insights into the clinico-biological characteristics of the consensus molecular subtype (CMS) CMS4 colorectal cancer subgroup, the molecular pathways driving this subtype, and available diagnostic options. [Clinical Cancer Research] |
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| Bausch Health Canada, Inc. announced the first public drug plan listings for PrUCERIS® (budesonide) aerosol foam to treat mild to moderate distal ulcerative colitis in adults. [Bausch Health Canada, Inc.] |
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| Dr. Patrick Varley was awarded a one-year, $60,000 Institutional Research Grant that provides funding for a pilot study evaluating the effect of residential neighborhood disparities on colorectal cancer outcomes within the Veterans Health Administration system. [University of Wisconsin-Madison] |
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| Duke University School of Medicine – Durham, North Carolina, United States |
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| Baylor College of Medicine – Houston, Texas, United States |
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| University of Colorado – Aurora, Colorado, United States |
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| University of Kentucky – Lexington, Kentucky, United States |
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| University of Montpellier – Montpellier, France |
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