 | | Vol. 10.12 – 12 April, 2024 |
| |
|
|
| Using a Muc6 knockout mouse model, gastric organoids, and cell lines, the authors proposed that Golgi stress responses and aberrant glycans induced by mucin deletion were important drivers of gastric cancer.
[Gastroenterology] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Scientists performed single-cell RNA-seq and lineage tracing experiments and demonstrated that transient activation of p53 was required to properly reprogram damaged epithelial cells in response to severe radiation injury to promote tissue regeneration.
[Nature Communications] |
|
|
|
| Researchers developed an in vitro model whereby human colon fibroblasts were induced by specific cytokines and recapitulated key features of inflammation-associated fibroblasts in vivo.
[Science Advances] |
|
|
|
| Using an Apc-mutant mouse model, investigators reported that GSK3β inhibition countered the actions of Wnt antagonists on intestinal stem cells, resulting in impaired adenoma formation of telomere dysfunctional Apc-mutant cells.
[Developmental Cell] |
|
|
|
| The authors reported that polymerase theta (POLQ), a widely conserved DNA polymerase, positively regulated stem cell-like characteristics of gastric cancer (GC) cells. Knockdown of POLQ suppressed the stemness of GC cells in vitro and in vivo.
[Cell Death & Disease] |
|
|
|
| Scientists reported that FAM120A was upregulated in gastric cancer (GC) tissues and higher in cisplatin-resistant GC tissues, and its high expression was positively correlated with the poor outcome of GC patients.
[Communications Biology] |
|
|
|
|
| The authors introduce the disease-related functions of goblet cells, their relationship with Crohn’s disease, their possible mechanisms, and current Crohn’s disease treatments targeting goblet cells.
[Cell & Bioscience] |
|
|
|
|
| Dr. Eunyoung Choi was an inaugural recipient of an American Association for Cancer Research (AACR)-Debbie’s Dream Foundation Innovation and Discovery Grant. Dr. Choi and her research team seek to evaluate the potential of aberrant fatty acid metabolism as a novel druggable target in gastric cancer.
[Vanderbilt University Medical Center] |
|
|
|
|
| May 20, 2024
New York, New York, United States & Online |
|
|
|
|
|
| | Harvard University – Massachusetts, Cambridge, United States |
|
|
|
| | Cedars-Sinai Medical Center – Los Angeles, California, United States |
|
|
|
| | Monash University – Melbourne, Victoria, Australia |
|
|
|
| | Duke University School of Medicine – Durham, North Carolina, United States |
|
|
|
| | Baylor College of Medicine – Houston, Texas, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
