 | | Vol. 7.01 – 15 January, 2021 |
| |
|
|
| Scientists report that CREPT, a recently identified tumor-promoting protein, was required for the maintenance of murine intestinal stem cells. CREPT was preferably expressed in the crypts but not in the villi.
[Nature Communications] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| The authors showed that dietary raffinose metabolism to fructose coupled stress-induced gut microbial remodeling to intestinal stem cells renewal and epithelial homeostasis.
[Nature Communications] |
|
|
|
| Investigators employed microinjection, time-lapse microscopy, bacterial genetics, and barcoded consortium infections to describe the complete infection cycle of Salmonella enterica serovar Typhimurium in both human and murine enteroids.
[mBio] |
|
|
|
| Plumericin was evaluated for its ability to improve barrier function and to reduce apoptotic parameters during inflammation, both in intestinal epithelial cells, and in an animal experimental model of 2, 4, 6-dinitrobenzene sulfonic acid-induced colitis.
[Biomedicines] |
|
|
|
| Using various models of intestinal cryptosporidiosis, the authors found that Cryptosporidium infection caused suppression of mitogen-activated protein kinase signaling in infected murine intestinal epithelial cells.
[Microorganisms] |
|
|
|
| Tumor organoid technology was used to evaluate the ablative potential of CD44-targeted polymer nanoparticles using hyaluronic acid (HA) as the targeting agent and coating it onto hybrid donor acceptor polymer particles (HDAPPs) to form HA-HDAPPs.
[Scientific Reports] |
|
|
|
| Scientists employed RNA-sequencing to assess transcriptomic response to ethanol exposure in 3D organoid lines derived from healthy colon. Paired regression analysis identified 2,162 differentially expressed genes in response to ethanol.
[Scientific Reports] |
|
|
|
| Researchers investigated if proteasome inhibitors have therapeutic potential for colon carcinoma and how this is influenced by human cytomegalovirus (HCMV) infection. They showed by immunofluorescence and flow cytometry that the colon carcinoma cell line Caco-2 was susceptible to HCMV infection.
[Viruses-Basel] |
|
|
|
| Scientists showed that E. rectale endotoxin activated the transcription factor NF-κΒ, which regulated multiple aspects of innate and adaptive immune responses in normal colon epithelial cells.
[Gut Pathogens] |
|
|
|
|
| The authors summarize the latest scientific literature on the involvement of the Hippo pathway in inflammatory bowel disease (IBD) from the following perspectives that account for the IBD pathogenesis: intestinal epithelial cell regeneration, immune regulation, gut microbiota, and angiogenesis.
[Cell Death & Disease] |
|
|
|
|
| Leading BioSciences, Inc. announced that the FDA has granted Fast Track Designation to LB1148 for the treatment of postoperative gastrointestinal dysfunction associated with pediatric heart surgery.
[Leading BioSciences, Inc. (GlobeNewswire, Inc.)] |
|
|
|
|
| November 29 – December 1, 2021
Barcelona, Spain |
|
|
|
|
|
| | STEMCELL Technologies, Inc. – Burnaby, British Columbia, Canada |
|
|
|
| | Medical University of GdaÅ„sk – GdaÅ„sk, Poland |
|
|
|
| | Karolinska Institutet – Huddinge, Sweden |
|
|
|
| | Aichi Cancer Center – Nagoya, Japan |
|
|
|
| | University of Dundee – Dundee, Scotland, United Kingdom |
|
|
|
| | Daiichi Sankyo, Inc. – Basking Ridge, New Jersey, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
