| Vol. 8.36 – 14 October, 2022 |
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| The authors showed that the subset of intraepithelial lymphocytes that expressed γ and δ T cell receptor subunits promoted the viability of Paneth cells deficient in the Crohn’s disease susceptibility gene ATG16L1. [Nature] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers identified novel circRNAs that can control liver metastatic colorectal cancer and discovered two anti-metastatic circRNAs generated from PPFIA1. [Molecular Cancer] |
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| H2DCFDA staining, and Mito-Tracker Red staining were carried out to evaluate mitochondrial membrane potential, intracellular reactive oxygen species level, and mitochondrial morphology. [Cancer Cell International] |
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| Scientists utilized 3D printing and inverse molding techniques to form 3D spongy scaffold systems that resemble the intestinal crypt-villus microarchitecture. [ACS Biomaterials Science & Engineering] |
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| The authors tested the potency of morin to inhibit cancer stem cells. They found that morin had significantly reduced colon cancer cell proliferation, colony formation, migration, and colonospheroid formation in a dose-dependent manner. [Medical Oncology] |
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| Researchers studied the FEZF1-AS1/miR-92b-3p/ZIC5 axis. They detected the expression of FEZF1-AS1, miR-92b-3p, and ZIC5 via quantitative reverse transcription-PCR, and performed functional assays. [Molecular and Cellular Biochemistry] |
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| The authors review the regulatory roles of signaling pathways in gastric cancer potential biomarkers, and therapeutic targets with an emphasis on recent discoveries. [Signal Transduction and Targeted Therapy] |
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| Investigators present an overview of the current evidence supporting the role of neurotransmitters in colorectal cancer biology and treatment. [Oncogene] |
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| VectivBio Holding AG announced positive interim data from the company’s ongoing Phase II STARS Nutrition study evaluating the safety, pharmacokinetics, and efficacy of apraglutide, an investigational new drug, a next-generation, long-acting synthetic GLP-2 agonist, in adult patients with SBS-IF and CIC. [VectivBio Holding AG] |
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| Iterative Scopes announced that it has partnered with One GI®, a gastroenterology management services organization to bring its AI Recruitment technology to One GI’s clinical research.. [Iterative Scopes (Business Wire)] |
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| November 7 – 9, 2022 Singapore, Singapore |
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| Colgate University – Hamilton, New York, United States |
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| Brigham and Women’s Hospital – Boston, Massachusetts, United States |
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| University of Colorado Denver – Aurora, Colorado, United States |
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| CancerCare Manitoba Research Institute – Winnipeg, Manitoba, Canada |
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| The University of British Columbia – Vancouver, British Columbia, Canada |
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