Intestinal Cell News Volume 8.36 | Oct 14 2022

    0
    26







    2022-10-14 | ICN 8.36


    Intestinal Cell News by STEMCELL Technologies
    Vol. 8.36 – 14 October, 2022
    TOP STORY

    The γδ IEL Effector API5 Masks Genetic Susceptibility to Paneth Cell Death

    The authors showed that the subset of intraepithelial lymphocytes that expressed γ and δ T cell receptor subunits promoted the viability of Paneth cells deficient in the Crohn’s disease susceptibility gene ATG16L1.
    [Nature]

    AbstractPress Release
    View tips on how to share lab duties effectively.
    PUBLICATIONSRanked by the impact factor of the journal

    Two circPPFIA1s Negatively Regulate Liver Metastasis of Colon Cancer via miR-155-5p/CDX1 and HuR/RAB36

    Researchers identified novel circRNAs that can control liver metastatic colorectal cancer and discovered two anti-metastatic circRNAs generated from PPFIA1.
    [Molecular Cancer]

    Full Article

    Cirsiliol Regulates Mitophagy in Colon Cancer Cells via STAT3 Signaling

    H2DCFDA staining, and Mito-Tracker Red staining were carried out to evaluate mitochondrial membrane potential, intracellular reactive oxygen species level, and mitochondrial morphology.
    [Cancer Cell International]

    Full Article

    Crypt-Villus Scaffold Architecture for Bioengineering Functional Human Intestinal Epithelium

    Scientists utilized 3D printing and inverse molding techniques to form 3D spongy scaffold systems that resemble the intestinal crypt-villus microarchitecture.
    [ACS Biomaterials Science & Engineering]

    AbstractGraphical Abstract

    Morin Inhibits Colon Cancer Stem Cells by Inhibiting PUM1 Expression In Vitro

    The authors tested the potency of morin to inhibit cancer stem cells. They found that morin had significantly reduced colon cancer cell proliferation, colony formation, migration, and colonospheroid formation in a dose-dependent manner.
    [Medical Oncology]

    Abstract

    Constructed the ceRNA Network and Predicted a FEZF1-AS1/miR-92b-3p/ZIC5 Axis in Colon Cancer

    Researchers studied the FEZF1-AS1/miR-92b-3p/ZIC5 axis. They detected the expression of FEZF1-AS1, miR-92b-3p, and ZIC5 via quantitative reverse transcription-PCR, and performed functional assays.
    [Molecular and Cellular Biochemistry]

    Abstract
    Activate, expand, and differentiate your cells with cytokines, chemokines, and growth factors from STEMCELL Technologies.
    REVIEWS

    Signaling Pathways and Therapeutic Interventions in Gastric Cancer

    The authors review the regulatory roles of signaling pathways in gastric cancer potential biomarkers, and therapeutic targets with an emphasis on recent discoveries.
    [Signal Transduction and Targeted Therapy]

    Full Article

    Neurotransmitter Signaling: A New Frontier in Colorectal Cancer Biology and Treatment

    Investigators present an overview of the current evidence supporting the role of neurotransmitters in colorectal cancer biology and treatment.
    [Oncogene]

    Abstract
    INDUSTRY AND POLICY NEWS

    VectivBio Reports Positive Interim Clinical Data from STARS Nutrition, a Phase II Study Investigating Apraglutide in Short Bowel Syndrome with Intestinal Failure Patients (SBS-IF) with Colon-in-Continuity (CIC)

    VectivBio Holding AG announced positive interim data from the company’s ongoing Phase II STARS Nutrition study evaluating the safety, pharmacokinetics, and efficacy of apraglutide, an investigational new drug, a next-generation, long-acting synthetic GLP-2 agonist, in adult patients with SBS-IF and CIC.
    [VectivBio Holding AG]

    Press Release

    Iterative Scopes Partners with One GI® to Advance Gastrointestinal Care Through Artificial Intelligence

    Iterative Scopes announced that it has partnered with One GI®, a gastroenterology management services organization to bring its AI Recruitment technology to One GI’s clinical research..
    [Iterative Scopes (Business Wire)]

    Press Release
    FEATURED EVENT

    Frontiers in Cancer Science 2022

    November 7 – 9, 2022
    Singapore, Singapore

    > See All Events

    JOB OPPORTUNITIES

    Assistant Professor – Cellular and Molecular Neuroscience

    Colgate University – Hamilton, New York, United States

    Research Assistant – Epithelial Cells

    Brigham and Women’s Hospital – Boston, Massachusetts, United States

    Assistant/Associate Faculty Position – Cancer Research

    University of Colorado Denver – Aurora, Colorado, United States

    Assistant Professor – Leukemia, Ovarian, Colorectal, and Lung Cancer

    CancerCare Manitoba Research Institute – Winnipeg, Manitoba, Canada

    Graduate Student – Nanomedicine and Chemical Biology

    The University of British Columbia – Vancouver, British Columbia, Canada

    > See All Jobs

    Submit an article, publication, job or event
    Brought to you by
    stemcell-logo-for newsletter-2
    Intestinal Cell News Twitter