 | | Vol. 8.41 – 25 November, 2022 |
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| Investigators suggested a critical role of amino acid sensing pathways in driving colorectal cancer and highlighted translational implications of dietary protein interventions.
[Gastroenterology] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| circTDRD3, which was upregulated under hypoxic conditions, was identified and may serve as a prognostic biomarker and therapeutic target for patients with colorectal cancer.
[Oncogene] |
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| The preliminary screening of active ingredient of predominant Lactobacilli was performed by component feeding trial. The active ingredient was administered to intestinal stem cells in vivo and in vitro to confirm its direct regulation and explored the underlying mechanism.
[mSystems] |
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| Scientists revealed the functional significance of proteasome subunit alpha type 1 (PSMA1) in gastric cancer progression and the underlying mechanisms.
[Cell Death & Disease] |
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| As Lacticaseibacillus casei ATCC334 potentially affects microbial ecosystem, researchers studied whether it may improve radiation-induced intestinal injury in rats by modulating the gut microbiota-metabolite-barrier axis.
[Molecular Nutrition & Food Research] |
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| The anti-oxidant effects and anti-inflammatory effects of PEGylated pterostilbene micelles (PTENPs) were determined under in vitro and in vivo conditions. It was found that compared with free PTE, PTENPs could effectively ameliorate acute IBD with low toxicity.
[International Journal of Pharmaceutics] |
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| Investigators utilized siRNA RID1A to explore the influence of AT-rich interactive domain-containing protein 1A (ARID1A) silencing on epithelial to mesenchymal transition in colorectal cancer cells.
[Journal of Cellular and Molecular Medicine] |
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| Scientists presented an in vitro analysis of the effects of molecules secreted by Lactobacillus gasseri SF1183 on HCT116 cells, selected as a model of intestinal epithelial cells.
[Scientific Reports] |
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| Researchers explored the distribution of CD3 and γδ T cells in colon mucosal compartments in histologically inactive and active inflammatory bowel disease.
[Journal of Pathology Clinical Research] |
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| Investigators found that the protein level but not RNA level of ferritin heavy chain was upregulated in colon cancer using paired clinical samples.
[Biological Trace Element Research] |
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| Researchers provided a general overview of congenital diarrheas and enteropathies, including a historical perspective of the field and relationship to other monogenic disorders of the intestine.
[Human Genetics] |
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| As P2X7R may be a biomarker and potential therapeutic target for the development and prognosis of colorectal cancer, the authors review current research progress.
[Molecular Biology Reports] |
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| Morphic Therapeutic announced that the EMERALD-2 phase IIb study of MORF-057 in ulcerative colitis had commenced with the first patient receiving MORF-057.
[Morphic Therapeutics] |
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| Shanghai Junshi Biosciences Co., Ltd. announced that the application for additional indications of adalimumab injection for the treatment of Crohn’s disease, uveitis, polyarticular juvenile idiopathic arthritis, plaque psoriasis in children had been approved by the National Medical Products Administration.
[Shanghai Junshi Biosciences co., Ltd. (Globe Newswire)] |
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| April 6 – April 8
Estoril, Portugal |
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| | Centre for Oncology and Immunology – Hong Kong, Hong Kong |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | Philipps-University Marburg – Marburg, Germany |
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| | STEMCELL Technologies, Inc. – Boston, Massachusetts, United States |
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