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| Investigators demonstrated that TGF-β promoted colonic inflammation and related tumorigenesis in the absence of Smad family member 4 (Smad4).
[Advanced Science] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors reported that DAB2IP was mutated or selectively silenced in the vast majority of KRAS and BRAF mutant colorectal cancers. DAB2IP loss promoted tumor development by activating wild-type H- and N-RAS proteins.
[Cancer Research] |
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| Scientists characterized the extracellular pH-intracellular pH relationship in 66 colorectal cancer cell lines and identified the acid-loading anion exchanger 2 as a regulator of resting intracellular pH.
[Cell Reports] |
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| Gastric cancer (GC) expression microarray data indicated that HOXB9 was a prominent upregulated HOX member in GC samples significantly associated with clinical outcomes and advanced TNM stages.
[Journal Of Pathology] |
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| Investigators reported that preexisting and newly synthesized histones H3 and H4 are asymmetrically partitioned during the division of Drosophila intestinal stem cells.
[EMBO Reports] |
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| Researchers used network pharmacology, subcutaneous, and orthotopic transplanted colorectal tumor models to determine the effect of Pien Tze Huang on tumor metastasis.
[Cancer Gene Therapy] |
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| Scientists addressed telomere length (TL) dynamics in primary colorectal cancer (CRC) tumor tissues and corresponding liver metastases. TL was measured by multiplex monochrome real-time qPCR in paired samples of primary tumors and liver metastases along with non-cancerous reference tissues.
[Scientific Reports] |
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| The authors investigated the role of the ubiquitin E3 ligase MDM2 in affecting cell growth and chemosensitivity in colorectal cancer cells by modifying the transcription factor inhibitor of growth protein 3 (ING3).
[Carcinogenesis] |
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| One hundred seventy-one patients with locally progressive gastric adenocarcinoma who had undergone neoadjuvant chemotherapy and radical surgery were collected. Immunohistochemistry was used to detect the expression of FAP, CD10, and GPR77 in cancer-associated fibroblasts.
[BMC Cancer] |
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| Six pairs of matched colorectal cancer (CRC) and normal colorectal tissue samples were sequenced using the Affymetrix Clariom D array. Using RNA interference, the expression of thirteen circRNAs was knocked down in CRC cells.
[World Journal of Surgical Oncology] |
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| Up-to-date research on the role of circRNAs in colorectal cancer (CRC) was examined, focusing on their potential application in CRC diagnosis and targeted therapy, which would advance the knowledge of the functions of circRNAs in the development and progression of CRC.
[Cell Death & Disease] |
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| Scientists review the relationship between colorectal cancer and microRNA expression and provide strategies for exploring potential options for colorectal cancer treatment.
[Frontiers in Oncology] |
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| Google will embed its generative AI technology into computer systems at Mayo Clinic and other health systems to make it easier to search vast repositories of patient data and automate administrative tasks.
[STAT News] |
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| June 18 – 22, 2023
Keystone, Colorado, United States |
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| | The University of Lleida – Lleida, Spain |
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| | Malmö University – Malmö, Sweden |
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| | Wageningen University & Research – Wageningen, Netherlands |
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| | Centre for Oncology and Immunology – Hong Kong, Hong Kong |
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| | KU Leuven – Leuven, Belgium |
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