 | | Vol. 9.22 – 16 June, 2023 |
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| The authors established patient-derived tumor organoids and performed a drug test in 277 samples from 242 colorectal cancer patients who received FOLFOX or XELOX chemotherapy.
[iScience] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| To identify drugs that could enhance the efficacy of MEK inhibitors, researchers performed unbiased high-throughput screening using colorectal cancer spheroids.
[Molecular Cancer Therapeutics] |
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| Melatonin inhibited gastric cancer cell migration and soft agar colony formation. Magnetic-activated cell sorting was applied to isolate CD133+ cancer stem cells.
[Journal Of Cellular And Molecular Medicine] |
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| The cell proliferation capacity of HCT116 and SW480 cells was assessed using the CCK-8 and EdU assays. Cell apoptosis was tested through flow cytometry, and cell migration and invasion were examined using the transwell assay.
[Scientific Reports] |
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| Researchers described the common activation of the zinc finger transcription factor and Let-7 target PLAGL2 in colorectal cancer and found that it was a key driver of intestinal epithelial transformation.
[American Journal Of Physiology-Gastrointestinal And Liver Physiology] |
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| PFKFB2 was selected by metabolism polymerase chain reaction array from colorectal cancer cells under alkaline culture medium and acidic culture medium.
[Journal of Cancer Research and Clinical Oncology] |
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| Scientists evaluated the impact of allyl isothiocyanate on cell migration and invasion of human gastric cancer AGS cells in vitro.
[Environmental Toxicology] |
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| Researchers investigated the role of apolipoprotein E (apoE) in colorectal cancer (CRC) metastasis and identified the transcription factor and receptor of apoE involved in regulation of CRC metastasis.
[Biomolecules & Biomedicine] |
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| The antiproliferative effect of metformin was assayed using an MTS reagent and its ability to inhibit colony formation was demonstrated using a clonogenic assay.
[Cancer Management And Research] |
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| The authors investigated the function and clinical significance of FAT10 protein expression in colorectal cancer (CRC). Over-expression and knockdown experiments of FAT10 were developed to explore their effects on CRC cell migration and proliferation.
[Digestive Diseases and Sciences] |
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| Investigators address the colorectal cancer (CRC) and exosome complex associated with cancer development and progression, the impact of exosomes on CRC screening, and also highlight several exosomes with CRC clinical trials, as well as future directions of exosome-based CRC research.
[ACS Applied Bio Materials] |
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| Takeda and HUTCHMED Limited announced that the European Medicines Agency has validated and accepted for regulatory review the marketing authorization application for fruquintinib used for the treatment of adult patients with previously treated metastatic colorectal cancer.
[Takeda] |
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| June 25 – 30, 2023
Newry, Maine, United States |
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| | King’s College London – London, England, United Kingdom |
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| | University of Pittsburgh – Pittsburgh, Pennsylvania, United States |
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| | The University of Lleida – Lleida, Spain |
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| | Malm̦ University РMalm̦, Sweden |
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| | Universitätsklinikum Carl Gustav Carus Dresden – Dresden, Germany |
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