 | | Vol. 9.34 – 15 September, 2023 |
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| By using multiple conditional deletion mouse models and ex vivo cultured organoids, researchers found that lipolysis-stimulated lipoprotein receptor (LSR) elimination in intestinal stem cells resulted in the disappearance of Paneth cells without affecting the differentiation of other cell lineages
[Cell Reports] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists investigated the restorative effect and mechanism of Shen-Ling-Bai-Zhu-San on disturbed intestinal homeostasis in dextran sulfate sodium-induced colitis mice.
[Journal Of Ethnopharmacology] |
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| Researchers demonstrated that alteration in cholesterol levels increase the incidence of chemical carcinogen-induced colon polyp occurrence and tumor progression in mice.
[Cancer & Metabolism] |
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| To understand how partitioning defective 3 (Par3) is related to colorectal cancer (CRC), scientists investigated the role of Par3 in the development of CRC using an in vivo genetic approach.
[Molecular Carcinogenesis] |
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| The effect of oleanolic acid on intestinal diseases under stressful conditions and its possible mechanisms have been investigated.
[Journal Of Biochemical And Molecular Toxicology] |
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| Scientists established a mouse model of colon cancer cachexia (CAC) and categorized the mice into three groups: CAC, noncachexia cancer, and normal control. By performing nuclear magnetic resonance-based metabolomic profiling on mouse sera, they elucidate the metabolic properties of these groups.
[Acta Biochimica Et Biophysica Sinica] |
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| Researchers developed a pH-responsive drug delivery nanoplatform, Res@ZIF-8/TA NPs, which exhibited good biocompatibility and showed promise for in vitro cancer therapy.
[Journal Of Biomedical Materials Research Part B-Applied Biomaterials] |
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| Chemical compositions of two essential oils obtained from different parts of Seseli bocconei Guss. and of Seseli tortuosum subsp. maritimum Guss., wild endemic species of Sicily, were investigated.
[Fitoterapia] |
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| Investigators surveyed the effect of lipopolysaccharide on cell viability and gene expression of 55 molecular targets in human colon cancer cells.
[BMC Research Notes] |
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| The authors summarize the research on the treatment of inflammatory bowel disease by many natural plant polysaccharides, and provides a theoretical basis for the later treatment of polysaccharides on inflammatory bowel disease.
[International Journal Of Biological Macromolecules] |
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| Scientists systematically introduce the multiple roles of nucleotide-binding and oligomerization domain (NOD)-like receptors in regulating intestinal mucosal barrier homeostasis and focus on summarizing the activities and potential mechanisms of natural products against inflammatory bowel disease.
[Therapeutic Advances In Gastroenterology] |
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| Fight Colorectal Cancer’s Climb for a Cure event has achieved a remarkable milestone by raising $1 million to advance colorectal cancer research. All dollars raised by this event go toward funding high-impact colorectal cancer research.
[Fight Colorectal Cancer] |
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| October 2 – 4, 2023
Boston, Massachusetts, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | Norwegian University of Science & Technology – Trondheim, Norway |
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| | University of Oxford – Oxford, England, United Kingdom |
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| | University of Australia – Adelaide, South Australia, Australia |
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