 | | Vol. 9.45 – 1 December, 2023 |
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| Researchers reported that high expression of inhibitor of differentiation 1 (ID1) in tumor-associated macrophages correlated with poor outcomes in patients with colorectal cancer.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists reported that the Dishevelled-associated activator of morphogenesis 1 (Daam1) and its paralogue Daam2 asymmetrically regulated canonical and noncanonical Wnt signaling.
[Science Advances] |
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| Investigators revealed that upregulated methyltransferase-like 3 (METTL3) in colorectal cancer exerted both methyltransferase activity-dependent and -independent functions in gene regulation.
[Cell Death & Disease] |
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| Analysis of mouse and human IBD cohorts helped examine claudin-3 (CLDN3) expression in IBD. The causal role was determined by modeling CLDN3 loss of expression during experimental colitis.
[Gut Microbes] |
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| Scientists investigated the expression pattern of inducible nitric oxide synthase (iNOS) within crypts and explored its function in the homeostatic maintenance of the intestinal stem cell niche.
[Journal of Translational Medicine] |
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| The authors found that the evolutionarily conserved endoplasmic reticulum membrane protein complex negatively regulated intestinal stem cell proliferation and intestinal homeostasis.
[Development] |
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| Researchers indicated that CXC chemokine ligand 3 (CXCL3) was upregulated in colon adenocarcinoma and played a crucial role in the control of malignant behaviors of tumor cells.
[BMC Cancer] |
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| Investigators explored the mechanism by which circVMP1 regulated tumor glycolysis and its related pathways in promoting colorectal cancer cell proliferation and metastasis.
[Environmental Toxicology] |
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| To determine whether the protective effect of curcumin (CCM) on intestinal ischemia/reperfusion injury was mediated by epigenetic effects on Wnt/β-catenin signaling, the effect of CCM was examined in vivo and in vitro.
[Kaohsiung Journal Of Medical Sciences] |
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| The authors describe the functions played by B7 homolog 3 (B7-H3) in colorectal cancer from both immune and non-immune elements.
[Biochimica Et Biophysica Acta-Reviews On Cancer] |
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| AbbVie announced that the company will pay $10 billion to the biotech firm Immunogen for the acquirement of an approved treatment for ovarian cancer and buying into a burgeoning area of oncology.
[STAT] |
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| January 16 – 19, 2024
San Diego, California, United States & Virtual |
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| | Francis Crick Institute – London, England, United Kingdom |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | University of California San Francisco – San Francisco, California, United States |
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| | Armenian Bioinformatics Institute – Yerevan, Armenia |
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| | NIH National Cancer Institute – Bethesda, Maryland, United States |
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