 | | Vol. 12.26 – 9 July, 2020 |
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| Researchers identified Aqp7 as a critical regulator of metabolic and signaling response to environmental cellular stresses in breast cancer, highlighting aquaporin-7 as a potential cancer-specific therapeutic vulnerability.
[Cancer Research] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors identified PTEN and DNA-PK as essential regulators of replication checkpoint arrest in response to AZD1775 and defined PTEN as a promising biomarker for efficient WEE1 cancer therapy.
[eLife] |
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| In a self-established mouse model consisting normal human breast tissues and normal human bone tissues, triple-negative breast cancer cell line SUM-1315 could spontaneously form species-specific bone metastasis.
[Cell Death & Disease] |
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| Investigators found that protease-activated receptor 1 was highly expressed in high invasive breast cancer cells, and predicted poor prognosis in ER-negative and high-grade breast cancer patients.
[Cell Death & Disease] |
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| In this study, the researchers performed intracranial injection using nine HER2-positive breast cancer cell lines to evaluate their proliferative activity in brain tissue.
[Cancers] |
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| Scientists showed that double thymidine block treatment efficiently arrested the EO771 cells in the S-phase without altering cell growth or survival.
[Bioessays] |
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| Researchers investigated the antitumor effects of polysaccharides from the fruiting body of S. vaninii and their associated mechanisms.
[International Journal of Biological Macromolecules] |
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| Investigators showed that Schizandrin A downregulated miR-155 and resulted in the suppression of proliferation and motility in breast cancer cells.
[LUBMB Life] |
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| Researchers evaluated the mechanisms associated to antitumor activity of 7-Epiclusianone, a tetraprenylated benzopenone, on luminal A and claudin-low breast cancer cell lines.
[Toxicology in Vitro] |
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| The author summarizes the recent in vitro, in vivo, and clinical studies investigating senescence in breast cancer treatments.
[Cancers] |
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| Halozyme Therapeutics, Inc. announced that the FDA has approved Roche’s Phesgo™ injection for the treatment of eligible patients with early and metastatic HER2-positive breast cancer. This is the first time a product has been approved combining two monoclonal antibodies that can be administered by a single subcutaneous injection utilizing Halozyme’s ENHANZE® technology.
[Halozyme] |
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| A new US immigration policy, which threatens to revoke visas for certain international students if they are not taking in-person classes, is stirring panic and confusion and causing some universities to push back with lawsuits.
[Science] |
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| September 9 – October 2
Barcelona, Spain |
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| | University of Pittsburgh – Pittsburgh, Pennsylvania, United States |
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| | Mayo Clinic – Rochester, Minnesota, United States |
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| | University of Oklahoma Health Science Center – Oklahoma City, Oklahoma, United States |
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| | University of Vermont – Burlington, Vermont, United States |
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| | Georgetown University Medical Center – Washington, District of Columbia, United States |
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