 | | Vol. 13.07 – 25 February, 2021 |
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| In two different stromal models and a 3D breast cancer spheroid model, the force spectrum analysis revealed emergent hybrid dynamics that involved both high-frequency stress stiffening and low-frequency fluidization of the extracellular matrix.
[Science Advances] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Knockdown of genes that function in multiple steps of cancer immunity was evaluated in aggressive triple-negative and HER2+ orthotopic, metastatic, and genetically engineered mouse breast cancer models.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| TET2 binding constituted a near-total subset of estrogen receptor-α binding in multiple breast cancer models, with loss of TET2 associated with reduced activation of proliferative pathways.
[Cell Reports] |
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| By using RNA-seq analysis, the authors found that nerve growth factor receptor was highly expressed in metastatic lung clones of MDA-MB-231 cells.
[Oncogene] |
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| Scientists confirmed that Ring1b could downregulate E-cadherin and contributed to an epigenetic rewiring via PRC1-dependent function by forming distinct complexes with DEAD-box RNA helicases or epithelial-mesenchymal transition (EMT) transcription factors on site-specific loci of E-cadherin promoter.
[Cell Death & Disease] |
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| Investigators report the development of novel endoxifen-resistant breast cancer cell lines and extensively compared these models to 4-hydroxy-tamoxifen and fulvestrant-resistant models.
[Molecular Cancer Research] |
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| In MDA-MB-231 cells, modulation of V1G1 affected cell migration and matrix metalloproteinase activation in vitro, processes important for tumor formation and dissemination.
[Scientific Reports] |
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| Researchers determined the exact nature and extent to which mitochondrial function was influenced by doxorubicin–transferrin conjugate treatment, specifically in human breast adenocarcinoma cells.
[Scientific Reports] |
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| Scientists discuss the recent advancements of molecular pathways involving breast cancer cell dissemination, role of chemokine-chemokine receptor networks in disseminated cancer cells (DCCs) migration, DCCs phenotypic heterogeneity, and unique gene signatures in tumor dormancy, microenvironmental regulation, and specific niches that favors DCCs homing and dormancy.
[Seminars in Cancer Biology] |
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| The authors focus on the role of exosomes in breast cancer, in terms of breast cancer biology, mechanism of action, potential as biomarkers, and therapeutic opportunities.
[Molecular Cancer Research] |
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| FibroGenesis announced new data supporting utilizing its fibroblast-based immunotherapy for successful inhibition and induction of regression in preclinical models of breast cancer and pancreatic cancer.
[FibroGenesis] |
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| Theralink Technologies, Inc. was named commercial provider of its patented Reverse Phase Protein Array technology for breast cancer patients, if the proposed study has a positive outcome.
[Theralink Technologies, Inc. (PR Newswire, LLC)] |
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| September 5 – 8, 2021
Exeter, England, United Kingdom |
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| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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| | Institute of Cancer Research – London, England, United Kingdom |
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| | German Cancer Research Center in the Helmholtz Association – Heidelberg, Germany |
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| | CyberCoders – San Diego, California, United States |
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| | University of Notre Dame – Notre Dame, Indiana, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
