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| Researchers showed that the extracellular vesicle signature had high accuracy for discrimination of metastatic breast cancer, non-metastatic breast cancer, and healthy donors.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors reported that exposure of human breast cancer cells to hypoxia activated epidermal growth factor receptor (EGFR) signaling was mediated by the hypoxia-inducible factor-dependent expression of a disintegrin and metalloprotease 12 (ADAM12).
[Proceedings of the National Academy of Sciences of the United States of America] |
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| Researchers identified a lncRNA LINC00926 negatively correlated with phosphoglycerate kinase 1 (PGK1) and predicting a good clinical outcome of breast cancer.
[Molecular Therapy] |
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| Investigators used mass cytometry to characterize the single-cell signaling landscapes of 62 breast cancer cell lines and five lines from healthy tissue.
[Cell Systems] |
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| Scientists screened all ten asparagine-linked glycosylation (ALG) members in breast cancer patients’ samples by RT-PCR. Cell viability after irradiation was determined by CCK-8 assay and flow cytometry.
[Journal of Experimental & Clinical Cancer Research] |
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| The authors identified a novel lncRNA 408 (lnc408) in epithelial-mesenchymal transition-related breast cancer stem cells (BCSCs). The lnc408 was highly expressed in BCSCs in vitro and in vivo.
[Cell Death & Disease] |
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| Investigators tested the anti-proliferative activity of capsanthin with human TNBC and found that cell proliferation was inhibited after 24, 48, and 72 h of treatment.
[Aging] |
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| The expression and signaling activity of HER2, HER3, and downstream pathway proteins were studied in cell panels representing HER2-amplified cancers of the breast, bladder, colon and rectal, stomach, esophagus, lung, tongue, and endometrium along with controls lacking HER2 amplification.
[Scientific Reports] |
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| The cell and dose-dependent cytotoxicity of few-layer black phosphorus and its bioconjugates was evaluated against HB2, MCF-7, and MDA-MB-231 cell lines.
[Scientific Reports] |
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| Investigators suggested that CD200 and CD276 were candidate inhibitory immune checkpoints in breast cancer stem cells, which were potentially regulated by Wnt, TGF‐β, and Hedgehog signaling.
[Cancer Medicine] |
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| The authors discuss various nanomedicines designed to selectively target breast cancer, TNBC, and breast cancer stem cells.
[International Journal of Molecular Sciences] |
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| Scientists discuss the current status of research into small molecular inhibitors against D-3-phosphoglycerate dehydrogenase in colorectal cancer, breast cancer, and Ewing’s sarcoma.
[Cell Death Discovery] |
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| GE Healthcare announced the acquisition of Zionexa. The company aims to develop and bring to market Zionexa’s pipeline biomarkers, as well as the recently FDA-approved PET imaging agent, Cerianna™ , which is used as an adjunct to biopsy for the detection of estrogen receptor positive lesions to help inform treatment selection for patients with recurrent or metastatic breast cancer.
[GE Healthcare] |
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| March 13 – 18, 2022
Ventura, California, United States |
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| | Karolinska Institutet – Solna, Sweden |
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| | University of Texas Southwestern Medical Center – Dallas, Texas, United States |
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| | University of Southampton – Southampton, England, United Kingdom |
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| | King’s College London – London, England, United Kingdom |
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| | The University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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