 | | Vol. 14.13 – 7 April, 2022 |
| |
|
|
| Researchers depicted an interplay of molecular, cellular, and tissue microenvironment alterations that increased BRCA1-associated breast cancer risk.
[Nature Communications] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Scientists reported that estrogen receptor (ER)-positive breast cancers had lower hyaluronan synthase 2 antisense RNA 1 (HAS2-AS1) expression compared to ER-negative tumors. The survival of patients with ER-negative tumors was higher when the expression of HAS2-AS1 was elevated.
[Matrix Biology] |
|
|
|
| The authors showed that high FER levels were associated with improved outcomes after adjuvant taxane-based combination chemotherapy in high-risk, HER2-negative patients.
[Cell Reports] |
|
|
|
| Investigators showed that when Hsp70-binding protein 1 (HspBP1) was either knocked down or overexpressed in BRCA1-proficient breast cancer cells, there were profound changes in tumorigenesis, including anchorage-independent cell growth in vitro and in tumor formation in xenograft models.
[Cell Death & Disease] |
|
|
|
| qRT-PCR was used to detect the expression of circular RNA_0006014 (hsa_circ_0006014) and related genes. MTT, colony formation and Transwell assays were used to explore the potential biological functions of hsa_circ_0006014 in breast cancer cells.
[Aging] |
|
|
|
| Breast cancer-related miRNA and mRNA microarray data sets were retrieved for differential analyses. Subsequently, the expression patterns of miR-4731-5p, PAICS, and FAK in breast cancer tissues and cells were determined.
[Cell Death Discovery] |
|
|
|
| The authors presented the first report that circular RNA RPAP2 (circRPAP2) was downregulated in breast cancer tissue samples and cell lines.
[Cell Death Discovery] |
|
|
|
| Researchers analyzed in vitro the effect of lysophosphatidic acid (LPA)18:1 and the LPA receptor 1 (LPAR1), LPAR3, and LPAR2 inhibitor Ki16425 on cellular functions of different human breast cancer cell lines and the human breast epithelial cell line, as well as Interleukin 8 (IL-8), IL-6 and tumor necrosis factor-alpha cytokine secretion after LPA-incubation.
[Scientific Reports] |
|
|
|
| The role of multiple epidermal growth factor like domains 11 (MEGF11) was studied in human TNBC MDA-MB-231 and MDA-MB-468 cells by overexpressing MEGF11 using non-attached culture.
[Life Sciences] |
|
|
|
| FHS-1 was synthesized utilizing excited-state intramolecular proton transfer to detect H2S in MCF-7 cells and investigated the effects of varying concentrations of NaHS on apoptosis.
[Future Medicinal Chemistry] |
|
|
|
|
| Investigators discuss in detail the divergence of early metastases as circulating tumor cells and the involvement of miRNAs as detectable blood-based diagnostic biomarkers that warrant a timely screening of cancer.
[Molecular Cancer] |
|
|
|
| The authors present how field cancerization presents itself pathologically and molecularly within histologically normal peri-tumoral tissues and discuss how using peri-tumoral tissues can affect research.
[Journal of Pathology] |
|
|
|
|
| Ion Beam Applications S.A. (IBA), and the University Medical Center (UMC) Groningen announced a four-year research collaboration agreement towards the development of a new FLASH irradiation protocol for the treatment of early-stage breast cancer.
[Ion Beam Applications S.A.] |
|
|
|
|
| BriaCell Therapeutics Corp., announced that its novel off-the-shelf (OTS) personalized immunotherapy, Bria-OTS™, is currently being manufactured at a cGMP facility and undergoing quality control testing for the potential upcoming clinical trial for patients with advanced breast cancer.
[BriaCell Therapeutics Corp.] |
|
|
|
|
| May 15 – 17, 2022
Sitges, Spain |
|
|
|
|
|
| | Cancer Research UK Beatson Institute – Glasgow, Scotland, United Kingdom |
|
|
|
| | Augusta University – Augusta, Georgia, United States |
|
|
|
| | Icahn School of Medicine at Mount Sinai – New York, New York, United States |
|
|
|
| | The University of British Columbia – Vancouver, British Columbia, Canada |
|
|
|
| | Case Western Reserve University – Cleveland, Ohio, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
