Mammary Cell News Volume 14.26 | Jul 14 2022

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    2022-07-14 | MCN 14.26


    Mammary Cell News by STEMCELL Technologies
    Vol. 14.26 – 14 July, 2022
    TOP STORY

    EBF1 Promotes Triple-Negative Breast Cancer Progression by Surveillance of the HIF1α Pathway

    Scientists demonstrated that early B cell factor 1 (EBF1) was highly expressed in TNBC cells, and the knockdown of EBF1, blocked TNBC cell growth and invasiveness.
    [Proceedings of the National Academy of Sciences of the United States of America]

    Abstract
    STEMCELL has implemented an Environmental Management System that is now ISO 14001-certified.
    PUBLICATIONSRanked by the impact factor of the journal

    LRP-1 Receptor Combines EGFR Signaling and eHsp90α Autocrine to Support Constitutive Breast Cancer Cell Motility in Absence of Blood Supply

    Investigators showed that LRP-1 orchestrated two parallel cell surface signaling pathways to support the full constitutive tumor cell migration.
    [Scientific Reports]

    Full Article

    Transcription Factor KLF16 Activates MAGT1 to Regulate the Tumorigenesis and Progression of Breast Cancer

    Researchers explored the role of magnesium transporter protein 1 (MAGT1) in breast cancer and illustrated the potential underlying molecular mechanisms.
    [International Journal of Molecular Medicine]

    Abstract

    Apigenin Alleviates Resistance to Doxorubicin in Breast Cancer Cells by Acting on the JAK/STAT Signaling Pathway

    The authors evaluated the effect of Apigenin on Doxorubicin (DOX) resistance in MCF-7 cells and a DOX-resistant MCF-7 cell line was developed by treating MCF-7 cells with increasing concentrations of DOX.
    [Molecular Biology Reports]

    Abstract

    MiR-589-5p Inhibits Cell Proliferation by Targeting Histone Deacetylase 3 in Triple Negative Breast Cancer

    Researchers investigated the impact of miR-589-5p/ HDAC3 axis on cancer cell development in TNBC cells.
    [Archives of Medical Research]

    Abstract

    Yin Yang 1 Promotes Aggressive Cell Growth in High-Grade Breast Cancer by Directly Transactivating Kinectin 1

    High Yin Yang 1 expression correlated positively with pathological progression and poor prognosis of high-grade breast cancer.
    [MedComm]

    Full Article
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    REVIEWS

    “Shedding” Light on HER4 Signaling in Normal and Malignant Breast Tissues

    The author gives an overview of the role of HER4 in normal and malignant breast epithelial cells and tissues.
    [Cellular Signalling]

    Full Article
    INDUSTRY AND POLICY NEWS

    Amazon Launches Cancer Vaccine Clinical Trial in Partnership with Fred Hutchinson

    Amazon has begun the development of cancer vaccines in collaboration with the Fred Hutchinson Cancer Research Center, and it recently launched an FDA-approved clinical trial.
    [CNBC LLC]

    Press Release
    FEATURED EVENT

    Advances in Therapeutic Applications of Stem Cells

    December 8 – 10, 2022
    Los Angeles, California, United States

    > See All Events

    JOB OPPORTUNITIES

    Postdoctoral Researcher – Brain Metastasis from Lung and Breast Cancers

    Hershey College of Medicine – Hershey, Pennsylvania, United States

    Postdoctoral Positions – Tumor Metabolism

    Université catholique de Louvain – Brussels, Belgium

    Postdoctoral Position – Cancer Research

    Albert Einstein College of Medicine – Bronx, New York, United States

    Postdoctoral Fellows – Bioinformatics

    Memorial Sloan Kettering Cancer Center – New York, New York, United States

    Computational Postdoctoral Position – Microbiome & Therapy Response

    German Cancer Research Center in the Helmholtz Association – Heidelberg, Germany

    > See All Jobs

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