 | | Vol. 14.47 – 15 December, 2022 |
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| Researchers conducted a phosphoproteomic screening of samples from HER2-negative female breast cancer receiving neoadjuvant paclitaxel, aiming to find candidate biomarkers of paclitaxel sensitivity.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists identified miR-1304-3p as the most upregulated microRNA in African American patients. Importantly, its expression significantly correlated with poor progression-free survival in African American patients.
[Nature Communications] |
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| Investigators showed that breast tumors surviving chemotherapy activate complex programs of immune modulation. Characterization of residual disease revealed distinct tumor cell populations.
[Nature Cancer] |
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| Researchers identified nuclear prelamin A recognition factor (NARF) as a hypoxia-inducible, hypoxia-inducible factor 1 target gene in human breast cancer cells.
[Science Advances] |
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| To improve the understanding of ERα structure-transcriptional relationships, scientists developed a series of chemically unconventional antagonists based on the antiestrogens elacestrant and lasofoxifene.
[npj Breast Cancer] |
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| The authors identified that loss of AKTIP, which is located on 16q12.2, drove tumorigenesis of estrogen receptor alpha (ERα)-positive, but not ERα-negative, breast cancer cells and was associated with poor prognosis of patients with ERα-positive breast cancer.
[Cell Reports] |
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| The effects of zearalenone and its metabolites α-zearalenol and β-zearalenol on the formation of carcinogenic estrogen-catechols in MCF-7 cells were investigated.
[Mycotoxin Research] |
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| Adipose stem cells were differentiated into adipocytes, and the subsequent adipocyte conditioned media were evaluated for their fatty acid profile, adipokine secretion, and influence on proliferation, migration, and invasion on tumoral and normal human breast cell lines.
[Clinical and Translational Oncology] |
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| Dual-specificity phosphatase 28 (DUSP28) level was identified by qRT-PCR and western blot assays. The proliferation, migration, and invasion of DUSP28 in MCF-7 and MDA-MB-231 cells were assessed by Cell Counting kit-8, colony formation, and transwell assays.
[Acta Biochimica Polonica] |
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| The authors address the roles delivered by myoepithelial cells (MECs) in breast cancer progression and decipher the molecular mechanisms regulating proper MECs’ physiology, integrity, and terminal differentiation.
[Cancer Cell International] |
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| Biomerica, Inc. received clearance from the Kingdom of Saudi Arabia Food and Drug Administration (KFDA), and the UAE Ministry of Health and Prevention for the EZ Detect™ Colon Disease test and the Aware® Breast Self Exam device.
[Biomerica, Inc.] |
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| May 11 – 13, 2023
Berlin, Germany |
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| | Institute of Cancer Research – London, England, United Kingdom |
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| | Institute of Cancer Research – London, England, United Kingdom |
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| | UC Davis School of Medicine – Davis, California, United States |
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| | Novartis – East Hanover, New Jersey, United States |
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| | Case Western Reserve University – Cleveland, Ohio, United States |
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